目的 探讨递进式策略治疗重症急性胰腺炎腹膜后感染的疗效.方法 回顾性分析第四军医大学西京消化病医院治疗的94例重症急性胰腺炎腹膜后感染的患者资料,其中传统治疗方法38例,递进式策略治疗方法56例.比较两种治疗方法的并发症、住院天数、病死率情况.结果 与传统治疗方法相比,递进式策略治疗方法病死率(4/56 vs 8/38,P=0.047)、并发症(6/56 vs 12/38,P=0.029)均低于传统治疗组,新发糖尿病(10/56 vs 6/38,P=0.048)高于传统治疗组.结论 对于重症急性胰腺炎腹膜后感染递进式策略治疗是一种有效的方法,能明显减少手术并发症,提高治疗成功率.
Objective To investigate the the efficacy of step-up approach for retroperitoneal infection in patients with severe acute pancreatitis.Methods The clinical data of 94 patients with SAP complicated with retroperitoneal infection who were admitted to our hospital were analyzed retrospectively.Patients were divided into 2 groups:routine therapy group(38 patients) and step-up approach group(56 patients).The demographic characteristic,operation complications,hospital stays and mortality were compared between the two groups.Results Compared with routine therapy group,the step-up approach group had lower incidence of operation complications (6/56 vs 12/38,P =0.029) and mortality (4/56 vs 8/38,P =0.047),higher rate of new-onset diabetes (10/56 vs 6/38,P =0.048).Conclusions Compared with the routine therapy,the step-up approach reduces the incidence of postoperative complications and the rate of mortality.