中文摘要：

背景：贴壁生长的细胞通过肌动-肌球蛋白之间的相互作用对细胞外基质或基底施加一定的牵张力,该过程与许多生理和病理过程密切相关。目的：综述了目前几种主要的细胞牵张力技术的基本原理及应用情况。方法：第一作者以＂细胞牵张力、细胞力学＂检索CNKI数据库、万方数据库,以＂Cell traction force、Biomechanics＂检索PubMed数据库、SpringerLink数据库。收入有关细胞牵张力测量方法的研究,排除重复研究。通过阅读,最终选取30篇文献进行综述,其中中文1篇,英文29篇。结果与结论：细胞牵张力的测量方法主要有3种：硅胶薄膜测量法、细胞牵张力显微镜技术、微组装悬臂梁。准确估算细胞牵张力,将进一步拓展对细胞-细胞以及细胞-微环境之间的力学作用等诸多基本问题的理解。

英文摘要：

BACKGROUND： Traction force generated by adherent cells exerts on the extracellular matrix or cell substrate through the interaction between actin and myosin, which involves a variety of physiological and pathological processes.OBJECTIVE： To review the fundamental principles and application of several traction force techniques.METHODS： The first author retrieved the databases of CNKI, WanFang, PubMed and SpringerLink for the research addressing the measurements of traction force using the keywords of ＂cell traction force, biomechanics＂ in Chinese and English, respectively. Repetitive articles were excluded, and 30 literatures were enrolled for analysis, including 1 Chinese and 29 English articles.RESULTS AND CONCLUSION： There are three kinds of measurements of traction force, such as silica gel membrane, traction force microscopy, and micromachined levers. The precise measurement of traction force contributes to further understand the cell-cell and cell-microenvironment mechanical interactions.