欢迎您！东篱公司
退出
-
申报数据库
-
立项数据库
-
成果数据库
-
项目获奖数据库
中文摘要：
利用自行设计合成的手性多齿胺膦配体L1～L8，分别与钌、铱、铁、钛和钒等金属络合物原位组合形成催化体系，用于消旋亚砜的氧化动力学拆分反应．结果表明，手性四齿胺膦配体L8与VO（acac）。组合的体系表现出较好的活性和中等程度的对映选择性．进而研究了温度、时间和溶剂对反应的影响．以三氯甲烷作溶剂，双氧水为氧化剂，在0．01mmol催化剂用量下，-10℃时，消旋苯甲亚砜氧化动力学拆分的对映选择性达到54％ce．这项研究是手性胺膦配体在消旋亚砜动力学拆分反应中的首次应用．
英文摘要：
The catalyst systems generated in situ from chiral aminophophine ligands L1-L8 and ruthenium,iridium,iron,titanium or vanadium complexes were used for the oxidative kinetic resolution of phenyl methyl sulfoxide. The chiral diaminodiphosphine ligand L8 exhibited good activity and moderate enantioselectivity. The effects of reaction temperature, time and solvent on the oxidative ki- netic resolution were further investigated. Using H202 as oxidant,the oxidative kinetic resolution of racemic phenyl methyl sulfoxide catalyzed by 0.01 mmol L8/VO（acac）2 proceeded smoothly in CHCl3 ,obtaining （R）-sulfoxide with 54% ee at --10℃ for 16 h. Fur- thermore,it was shown that the oxidative kinetic resolution of the raeemic sulfoxides carried out in CHCl3 gave better enantioselectiv- ities than those in CH2 Cl2.
同期刊论文项目
同项目期刊论文
Supported monodisperse Pt nanoparticles from Pt-3(CO)(3)(mu(2)-CO)(3) (5)(2-) clusters for investiga
Cu24O24Si8R8: Organic Soluble 56-Membered Copper(I) Siloxane Cage and Its Use in Homogeneous Catalys
Probing Stepwise Reaction of NNP-Ligand Copper(I) Complex with Elemental Sulfur by Using N-Heterocyc
Structure and catalytic performance of alumina-supported copper-cobalt catalysts for carbon monoxide
Highly efficient mesostructured Ag/SBA-15 catalysts for the chemoselective synthesis of methyl glyco
Bronsted acidic ionic liquid as an efficient and recyclable promoter for hydroesterification of olef
Copper-catalyzed propylene epoxidation by oxygen Significant promoting effect of vanadium on unsuppo
Iron-Catalyzed Highly Enantioselective Reduction of Aromatic Ketones with Chiral P2N4-Type Macrocycl
Spectroscopic and DFT Study on the Interaction System of Vanadium with L-Proline in Aqueous Solution
Trends in R-X Bond Dissociation Energies (R-center dot = Me, Et, i-Pr, t-Bu, X-center dot = H, Me, C
Theoretical studies of Na+ location in ZSM-5: Model selection for accurate coordination structure an
Acid-catalysed direct transformation of cellulose into methyl glucosides in methanol at moderate tem
Exploring the Sodium Cation Location and Aluminum Distribution in ZSM-5: A Systematic Study by the E
Conversion of cellobiose into sorbitol in neutral water medium over carbon nanotube-supported ruthen
Production of ethanol by gas phase hydrogenation of acetic acid over carbon nanotube-supported Pt-Sn
PVP-stabilized heteropolyacids as reusable self-assembling catalysts for alcoholysis of cellulosic s
DCMB that Combines Divide-and-Conquer and Mixed-Basis Set Methods for Accurate Geometry Optimization
Cu/SiO2 hybrid catalysts containing HZSM-5 with enhanced activity and stability for selective hydrog
An efficient Ni-Mo-K sulfide catalyst doped with CNTs for conversion of syngas to ethanol and higher
Improved performance of magnetically recoverable Ce-promoted Ni/Al2O3 catalysts for aqueous-phase hy
Electronic Properties and Desolvation Penalties of Metal Ions Plus Protein Electrostatics Dictate th
Influence of the support and promotion on the structure and catalytic performance of copper-cobalt c
Vapor-phase hydrogenation of dimethyl oxalate over a CNTs-Cu-SiO2 hybrid catalyst with enhanced acti
Synthesis of novel chiral tetraaza ligands and their application in enantioselective transfer hydrog
A boracite metal-organic framework displaying selective gas sorption and guest-dependent spin-crosso
Na+-intercalated carbon nanotubes-supported platinum nanoparticles as new highly effective catalysts
Nonfitting protein-ligand interaction scoring function based on first-principles theoretical chemist
Novel chiral C-2-symmetric multidentate aminophosphine ligands for use in catalytic asymmetric reduc
期刊信息
位置：