中文摘要：

目的分析1990年与2013年中国甲状腺癌的疾病负担变化情况。方法利用2013年中国分省疾病负担研究数据，采用发病率、死亡率、过早死亡损失寿命年（YLL）、伤残损失寿命年（YLD）及伤残调整寿命年（DALY）作为测量疾病负担的主要指标，比较1990年与2013年中国甲状腺癌的疾病负担变化情况。结果2013年中国甲状腺癌的发病人数为33939例，与1990年相比增加21898例，标化发病率由1990年的1．25／10万升至2．07／10万，增加65．6％，其中女．f生发病率上升，男性发病率下降。2013年中国因为甲状腺癌死亡4974例，比1990年增加1810例，标化死亡率下降14．29％，其中女性死亡率下降而男性死亡率上升。中国女性甲状腺癌发病率随着年龄的增加而上升，50～54岁年龄组达到高峰。男性甲状腺癌发病率随着年龄增加一直呈现上升趋势。男女性甲状腺癌的死亡率均随年龄的增大而升高。2013年中国因甲状腺癌造成的DALY、YLL、YLD分别为13．35、11．42、1．93万人年，与1990年相比总体DALY标化率由10．33／10万降至8．84／10万，其中YLL标化率由9．60／10万降至7．61／10万，YLD标化率由0．72／10万升至1．23／10万。2013年中国甲状腺癌发病率前三位的省份为青海、新疆和福建，最低的为西藏；与1990年相比，除天津市外各省份发病率均上升；死亡率前三位的省份为青海、香港和福建，最低的为西藏，5个省份死亡率上升。结论与1990年相比，2013年甲状腺癌的总体标化发病率上升，标化死亡率下降；虽然DALY下降，但由甲状腺癌伤残导致的疾病负担仍然处于上升趋势。

英文摘要：

Objective To analyze the disease burden of thyroid cancer in the Chinese population, in 1990 and 2013. Methods Data on China from the Global Burden of Disease 2013 （GBD2013） was used to analyze the related parameters as mortality, prevalence,years of life lost due to premature mortality （YLL）, years lived with disability （YLD） and disability-adjusted life years （DALY） of thyroid cancer in China in 1990 and 2013 among all the Chinese population. Results There were 33 939 thyroid cancer patients identified in 2013 （7 146 men and 26 793 women）, with an increase of 21 898 patients than the number in 1990. The incidence rate of thyroid cancer increased by 181.86%. The incidence rates of thyroid cancer showed an increase in females but a decrease in males. In 2013, 4 974 people （2 292 men and 2 682 women） died of thyroid cancer, with an increase of 1 810 patients, compared with the figures in 1990. The mortality rate of thyroid cancer in 2013 decreased by 14.29%, compared with the figures in 1990. The mortality rate of thyroid cancer decreased in females while the incidence rate in males showed an increase. The incidence rates increased with age in females, reaching a peak at the 50-54 years old group. The mortality rate of thyroid cancer increased with age. The DALY, YLL and YLD due to thyroid cancer appeared as 13.35, 11.42 and 1.93 ten thousand person years, respectively, in 2013. Between 1990 to 2013, the age-standardized rates on DALY, YLL and YLD decreased from 10.33/100 000 to 8.84/100 000, from 9.60/100 000 to 7.61/100 000 and increased from 0.72/100 000 to 1.23/100 000, respectively. In 2013 the top three incidence rates were recorded in Qinghai, Xinjiang and Fujian provinces while the lowest was in Tibet. Compared with those in 1990, the incidence rates increased in all the provinces except for Tianjin. The top three high mortality rates were recorded in Qinghai, Hong Kong and Fujian and the lowest was also in Tibet. The mortality rates increased in five provinces. Conclusions Compared