中文摘要：

目的了解早产儿巨细胞病毒（HCMV）、弓形虫（TOX）、乙肝病毒（HBV）、单纯疱疹病毒1型（HSV-1）、单纯疱疹病毒2型（HSV-2）、风疹病毒（RV）与柯萨奇病毒B组3型（CVB3）的感染状况。方法采用巢式PCR对122例早产儿和75例正常新生儿进行7种病原体核酸的筛查检测。结果早产儿HCMV感染率为63.9%、TOX感染率为3.3%,HBV感染率为9.8%,HSV-1感染率为4.9%,HSV-2感染率为6.6%,RV感染率为3.3%,CVB3感染率为23.8%。早产儿HCMV、HBV、HSV-2和CVB3感染率与正常新生儿HCMV、HBV、HSV-2、CVB3感染率29.3%、1.3%、0和0比较,差异有统计学意义（P〈0.05）。结论 HCMV、HBV、HSV-2和CVB3感染是早产儿发生的危险因素之一。

英文摘要：

Objective To determine the state of HCMV,TOX,HBV,HSV-1,HSV-2,RV,and CVB3 infection in premature infants.Methods Nested PCR was used to examine the nucleic acids of seven kinds of pathogens in 122 premature infants and 75 normal newborns.Results The infection rates of HCMV,TOX,HBV,HSV-1,HSV-2,RV,and CVB3 in premature infants were respectively 63.9%,3.3%,9.8%,4.9%,2 6.6%,3.3%,and 23.8%.The infection rates of HCMV,HBV,HSV-2,and CVB3 in premature infants were significantly higher than 29.3%,1.3%,0%,and 0% of normal neonates（P0.05）.Conclusion HCMV,HBV,HSV-2,and CVB3 infection are a risk factor in premature infants.