Separation,identification,and quantification of active constituents in Fructus Psoraleae by high-performance liquid chromatography with UV,ion trap mass spectrometry,and electrochemical detection
- 时间:0
- 分类:R28[医药卫生—中药学;医药卫生—中医学]
- 相关基金:supported by the National Mega Project on Major Drug Development (No. 2009ZX09301-014-1); the National Scientific Foundation of China (Nos. 90817103,20775055,30973672); the start-up funds for ZC’s Luojia chair professorship of Wuhan University (Nos. 306276216,306271159); the Fundamental Research Funds for the Central Universities
中文摘要:
The qualitative and quantitative analysis of active constituents in Fructus Psoraleae is presented by high-performance liquid chromatography (HPLC) coupled with different detections.Extracts of Fructus Psoraleae were examined by HPLC with ion trap mass spectrometry (IT-MS) and 18 major compounds of coumarins,benzofuran glycosides,flavonoids,and meroterpene were identified.The determination of four major constituents including bavachin,isobavachalcone,bavachinin,and bakuchiol was accomplished by HPLC with UV...