中文摘要：

报道了一种表面活性剂单分子层修饰碳糊电极,并用于NO的高灵敏电化学检测。研究表明,表面活性剂通过烷基链在电极表面形成的疏水性单分子层微环境对NO的电化学响应具有较好的促进作用。其中,阳离子表面活性剂十六烷基三甲基溴化铵（CTAB）对NO的电化学氧化表现出最强的催化活性和增敏作用。在Nafion膜覆盖的CTAB修饰碳糊电极上,NO的安培响应与其浓度在3.6×10-8～1.8×10-5mol/L范围内呈良好的线性关系,检出限为1.8×10-8mol/L。该电极作为低成本、高灵敏的NO电化学传感器,被成功应用于大鼠肺组织细胞中NO释放的实时监测。

英文摘要：

In this work,a novel electrochemical sensor of nitric oxide （NO） based on a surfactant self-assembled monolayer modified carbon paste electrode （CPE） was reported. The monolayer of surfactant on CPE was believed to create a hydrophobic microenvironment favorable to the accumulation of NO on CPE. A cationic surfactant,cetyltrimethylammonium bromide （CTAB）,exhibited the strongest catalytic activity and accumulation capacity for the electrochemical oxidation of NO at CPE. The amperometric response of NO at a Nafion film coated CTAB modified CPE was in a good linear relationship with its concentration in the range of 3.6×10-8~1.8×10-5 mol/L,along with a low detection limit of 1.8×10-8 mol/L （S/N=3）. This NO electrochemical sensor was successfully applied to the real-time monitoring of NO release from lung tissue cells of rat by the stimulation of L-argentine （L-Arg）.