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Dyslipidaemia among diabetic patients with ischemic stroke in a Chinese hospital
  • ISSN号:0366-6999
  • 期刊名称:《中华医学杂志:英文版》
  • 时间:0
  • 分类:TS218[轻工技术与工程—粮食、油脂及植物蛋白工程;轻工技术与工程—食品科学与工程] TS972.161
  • 作者机构:[1]Department of Endocrinology, Affiliated Zhongda Hospital of Southeast University, Nanjing, Jiangsu 210009, China, [2]Department of Neurology , Affiliated Zhongda Hospital of Southeast University, Nanjing, Jiangsu 210009, China, [3]Centre for Nephrology, Royal Free and University College Medical School, University College London, Royal Free Campus, London, UK
  • 相关基金:This work was partially supported by the National Natural Science Foundation of China (No. 30870870, WANG Shao-hua; No. 30600206, GUO Yi-jing) and Natural Science Foundation of Jiangsu Province (No. BK2008302, WANG Shao-hua).Acknowledgment: We would like to express our thanks to the nursing staff of the Division of Endocrinology, Zhongda Hospital of Southeast University, for their help.
中文摘要:

背景 Dyslipidaemia 是一个潜在的独立风险因素因为在有这研究的 diabetes.The 目的病人的脑血管的疾病是调查 dyslipidaemia ,在有 ischemic 的糖尿病的病人之中的 dyslipidaemia 的治疗和控制在中国 hospital.Methods 摸 2 个糖尿病的病人被分到糖尿病与的 1046 类型的一个总数( n=522 )并且没有中风 groups.The 的糖尿病二个组被性,年龄和糖尿病匹配 duration.Lipid 和脂蛋白侧面是 measured.Ser

英文摘要:

Background Dyslipidaemia is a potential independent The aim of this study was to investigate dyslipidaemia, with ischemic stroke in a Chinese hospital. risk factor for cerebrovascular disease in patients with diabetes. treatment and control of dyslipidaemia among diabetic patients Methods A total of 1046 type 2 diabetic patients were assigned to diabetes with (n=-522) and diabetes without stroke groups. The two groups were matched by gender, age and diabetes duration. Lipid and lipoprotein profile were measured. Serum level and control of lipids were assessed and classified according to American Diabetes Association (ADA) guidelines and an intensified low density lipoprotein-cholesterol (LDL-C) target recommended in Chinese dyslipidaemia control criteria. Results Diabetic patients suffering stroke displayed not only poorly-controlled lipid and lipoprotein profiles, including the significantly lower proportion of patients achieving intensified LDL-C target of 〈2.07 mmol/L (80 mg/dl), and high density lipoprotein-cholesterol (HDL-C) target (14.4% vs 21.0%, P=0.005; 45.8% vs 51.9%, P=0.048 respectively), but also less adherence to therapy prescribed for dyslipidaemia (30.8% vs 41.0%, P=0.001), when compared with diabetic patients without stroke. For the diabetic women with stroke, situation of dyslipidaemia was worse, with significantly lower serum level of HDL-C and apoA1, higher LDL-C level and higher ratio of apoB/apoA1 when compared with diabetic counterparts without stroke. Conclusions Many diabetic patients with ischemic stroke remain uncontrolled for dyslipidaemia. Intensified LDL-C and overall lipid lowering clinical goals are potential precautions taken against ischemic stroke among diabetic patients in China.

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期刊信息
  • 《中华医学杂志:英文版》
  • 中国科技核心期刊
  • 主管单位:中国科协
  • 主办单位:中华医学会
  • 主编:
  • 地址:北京东四西大街四十二号
  • 邮编:100710
  • 邮箱:cmj@cma.org.cn
  • 电话:010-85158321
  • 国际标准刊号:ISSN:0366-6999
  • 国内统一刊号:ISSN:11-2154/R
  • 邮发代号:2-920
  • 获奖情况:
  • 1997、1998、1999年获中国科协优秀科技期刊择优资...,1992、1997年连续两年荣获全国优秀科技期刊和中国...,中国期刊方阵双高期刊
  • 国内外数据库收录:
  • 美国化学文摘(网络版),英国农业与生物科学研究中心文摘,荷兰文摘与引文数据库,荷兰医学文摘,美国生物医学检索系统,美国科学引文索引(扩展库),美国生物科学数据库,日本日本科学技术振兴机构数据库,中国中国科技核心期刊
  • 被引量:3319