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Studies on the Synthesis of Imidazole-metal Complexes and Their Characterization and Binding Mechanism with DNA
  • ISSN号:1001-604X
  • 期刊名称:《中国化学:英文版》
  • 时间:0
  • 分类:O626.3[理学—有机化学;理学—化学]
  • 作者机构:[1]College of Chemistry and Molecular Engineering, Qingdao University of Science and Technology, Qingdao, Shandong 266042, China
  • 相关基金:Project supported by the Program for New Century Excellent Talents in University (Nos. NCET-04-0649), the National Natural Science Foundation of China (Nos. 20275020, 20475030) and the 0utstanding Adult-young Scientific Research Encouraging Foundation of Shandong Province, China (No. 2006BS03049).
中文摘要:

2,5-piperazinedione 的新衍生物, 1,4-di (2-methoxyphenyl )-2,5-piperazinedione (I) ,被 N-2-methoxyphenyl chloroacetamide,和它的结构的 cyclocondensation 反应综合被元素的分析,红外, 1H NMR 和单身者描绘水晶 X 光检查衍射方法。水晶属于单斜晶的系统,有统一房间尺寸 a=0.56934 (10 ) nm 的空格组 P21/c, b=1.3880 (2 ) nm, c=1.00329 (17 ) nm, =90.376 (3 )? e

英文摘要:

A new derivative of 2,5-piperazinedione, 1,4-di(2-methoxyphenyl)-2,5-piperazinedione (I), was synthesized by the cyclocondensation reaction of N-2-methoxyphenyl chloroacetamide, and its structure was characterized by elemental analysis, IR, ^1H NMR and single crystal X-ray diffraction method. The crystal belongs to monoclinic system, space group P21/c with unit cell dimensions a=0.56934(10) nm, b=1.3880(2) nm, c=1.00329(17) nm, β= 90.376(3)°, V= 0.7928(2) nm^3, Z=2, Dc = 1.367 g·cm^-3,μ = 0.98 cm^-1, R and wR being 0.0606 and 0.1564 respectively for 1549 unique reflections with 1247 observed reflections [I〉2σ(I)]. The molecule has a crystallographically imposed symmetry center. The three rings in the molecule are each coplanar with their attached groups, excluding methyl H atoms and the H atoms attached to the piperazinedione ring, while the whole molecule is not planar, with dihedral angles of 74.7(1)° between the piperazinedione and each of the two aromatic rings. The crystal structure is stabilized by van der Waals and dipole-dipole forces.

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期刊信息
  • 《中国化学:英文版》
  • 主管单位:
  • 主办单位:中国化学会
  • 主编:
  • 地址:上海市枫林路354号中科院上海有机化学研究所
  • 邮编:200032
  • 邮箱:
  • 电话:021-54925243
  • 国际标准刊号:ISSN:1001-604X
  • 国内统一刊号:ISSN:31-1547/O6
  • 邮发代号:4-646
  • 获奖情况:
  • 中国期刊方阵“双高”期刊
  • 国内外数据库收录:
  • 美国化学文摘(网络版),荷兰文摘与引文数据库,美国科学引文索引(扩展库),日本日本科学技术振兴机构数据库,英国英国皇家化学学会文摘
  • 被引量:175