中文摘要：

按生态学方法建立和培育模型池塘生态系统，选择符合要求的生态池分别添加0.8mg·L^-1、4．0mg·L^-1、20．0mg·L^-1和100mg·L^-1盐酸土霉素，定期采集水样和底泥样品，用高效液相色谱方法进行药物浓度测定．结果表明，水中药物在用药后消除迅速，其消除半衰期分别为27．32h、34．10h、45．25h、56．07h．底泥中土霉素消除较缓慢，底泥0。2cm表层中的土霉素消除半衰期分别为38．18d、36．75d、46．75d、33．38d．底泥2～4cm中的土霉素消除半衰期分别为53．45d、59．58d、47．17d、50．83d．结果提示，底泥中的土霉素大部分以原形药物形式存在，并有明显的从表层向下层迁移的过程；土霉素的浓度对底泥中土霉素的半衰期和平均滞留时问无明显影响．

英文摘要：

To study the regularity of oxytetracycline residue in the model pond ecosystem, four experimental ponds were selected, and 0.8 mg·L^-1, 4.0 mg·L^-1, 20.0 mg·L^-1 and 100 mg·L^-1 oxytetracycline hydrochloride were added, respectively. Water and sediment samples were collected at regular intervals and detected by HPLC method. The result indicated that oxytetracycline was eliminated quickly in water after treated, and the elimination half life of water was 27.32 h, 34.10 h, 45.25 h and 56.07 h, respectively. Oxytetracycline was eliminated slowly in sediment. The elimination half life of 0-2 cm surface sediment was 8.18 d, 36.75 d, 46.75 d and 33.38 d, and that of 2-4 cm deep sediment was 53.45 d, 59.58 d, 47.17 d and 50.83 d, respectively. It was concluded that most oxytetracyclin maintained as original shape in sediment and it could migrate from surface to lower layer in sediment. The content of oxytetracycline had no effect on both the elimination half life and mean retention time of oxytetracycline in sediment.