在家庭 Reoviridae 的病毒是包括包围由的一个分割的双 stranded RNA 染色体的非包的粒子一二分层或 multi-layered icosahedral 蛋白质衣壳。这些病毒基于他们的粒子被分类进二个亚科结构的组织。最近的研究由使用 cryo 电子显微镜学(cryo 他们) 接近在 X 光检查结晶的结构看见的决定集中了于 reovirus 粒子的高分辨率的三维的结构。cryo 他们图象重建的结果允许大多数蛋白质方面链跟踪,并且因此为 reovirus 汇编和入口允许结构、功能的信息的集成进协调机制。
Viruses in the family Reoviridae are non-enveloped particles comprising a segmented double-stranded RNA genome surrounded by a two-layered or multi-layered icosahedral protein capsid. These viruses are classified into two sub-families based on their particle structural organization. Recent studies have focused on high-resolution three-dimensional structures of reovirus particles by using cryo-electron microscopy (cryo-EM) to approach the resolutions seen in X-ray crystallographic structures. The results of cryo-EM image reconstructions allow tracing of most of the protein side chains, and thus permit integration of structural and functional information into a coherent mechanism for reovirus assembly and entry.