中文摘要：

目的：制备羧基功能化石墨烯修饰玻碳电极，研究芦丁在该电极上的电化学行为，建立芦丁测定的新方法。方法：分别采用循环伏安法和差示脉冲伏安法研究了芦丁在修饰电极上的电化学行为，优化了包括支持电解质、缓冲液pH、修饰剂用量等测定条件。结果：在10mmol／LpH=7．5的Tris-Hcl缓冲溶液中，还原峰电流与芦丁的浓度对数在4．0×10-7-8．0×10-5mol／L范围内呈良好的线性关系，检出限为1．0×10-7mol／L（S／N=3），加样回收率在97．60％-106．30％。结论：该方法灵敏度高、检测范围宽，已用于复方芦丁片中芦丁的测定，结果令人满意。

英文摘要：

Objective ： To prepare the glassy carbon electrode modified by carboxyl fimctionalized graphene and establish a novel method for the determination of rutin. Methods ： The electrochemical behavior of rutin on the glassy carbon electrode modified by carboxyl functionalized graphene was studied by voltammetry.The experimental parameters such as the supporting electrolyte, pH of buffer solution, the amount of carboxyl functionalized grapheme and the accumulation time were optimized in detail. Results ： It showed that the reduction peak currents varied linearly with the logarithm of the concentration of rutin over the range from 4.0 × 10-7 mol/L to 8.0 × 10-5 mol/L with the detection limit of 1.0 × 10-7 mol/L in pH value of 7.5 Tris-HC1 buffer solution （ S/N=3 ）. Conclusion ： The method has been successfidly used to detect rutin in compound rutin tablets and it is simple and accurate.