中文摘要：

骨髓增生异常综合征（MDS）是一组克隆}生造血干细胞性疾病。目前研究提示MDS患者端粒长度的变化与疾病的发生、发展关系密切。因此，端粒长度与MDS的关系和端粒长度的检测方法逐渐成为研究热点。文章对近年来在MDS端粒长度变化及检测方法的进展进行综述。

英文摘要：

Myelodysplastic syndromes （MDS） are a group of clonal disorders of hematopoietic stem cells. Recent studies have shown that the change of telomere length is closely related to the development and progression of MDS. Therefore, the dynamics of telomere length in MDS and the measurement methods of telomere length have been focused on gradualiy. Here the recent advances in this field were reviewed.