中文摘要：

通过热重法研究了抗结核药物丙硫异烟胺的热稳定性,计算了该药物的动力学参数并建立了热分解动力学方程.用Kissinger和Ozawa-Flynn-Wall两种方法计算该药物热分解过程的活化能Ea=54.65 kJ·mol^-1.用Malek法推断该药物的动力学机理函数及指前因子A,其结果分别为f（α）=α^0.391（1-α）^0.145,InA=13.12.此外,用差热法测定该物质的熔点、摩尔熔化焓和摩尔熔化熵,分别是414.09 K、23.21 kJ·mol^-1和56.06 J·mol^-1·K^-1.

英文摘要：

The thermal stability and the kinetics of thermal decomposition of protionamide were studied by thermogravimetry.Activation energy Ea of thermal decomposition of this substance was obtained to be 54.65 kJ·mo1^-1 by Kissinger method and Ozawa-Flynn-Wall method.Kinetics model function and frequency factor A of protionamide were predicted with the Malek method,which were f（α）=α^0.391（1-α）^0.145 and InA=13.12,respectively.Moreover,melting point,molar enthalpy and entropy of fusion of this compound were determined to be 414.09 K,23.21 kJ·mol^-1,and 56.06 J·mol^-1·K^-1,respectively.