中文摘要：

目的调查D7S3048等9个非DNA联合索引系统（combinedofDNAindexsystem，CODIS）指定的核心短串联重复序列（shorttandemrepeat，STR）基因座在广东汉族人群的遗传多态性。方法采用荧光标记复合扩增和毛细管电泳技术，对广东汉族500名无关个体的DNA进行9个STR基因座分型。结果500名无关个体在D7S3048等9个非CODIS核心STR基因座共检出115个等位基因，160种基因型，各基因座杂合度为0．824～0．884，个人识别能力为0．925～0．969，多态信息总量为0．77～0．86，均符合Hardy—Weinberg平衡（P〉0．05），9个STR基因座的累计个体识别力达1．00×10^-13，三联体累计非父排除率为0．999989488，二联体累计非父排除率为0．873436。结论D7S3048等9个STR基因座在个体识别及亲子鉴定中是一个高效的检测系统，在二联体亲子鉴定中可作为补充基因座满足疑难、单亲和突变案件的需求。

英文摘要：

Objective To investigate the genetic polymorphisms and their forensic application of 9 nomcombined of DNA index system （CODIS） short tandem repeat （STR） loci in Guangdong Hart population. Methods DNA samples from 500 unrelated individuals were extracted and amplified with fluorescence labeled multiplex PCR system. PCR products were separated and genotyped with capillary eleetrophoresis. Results One hundred and fifteen alleles and 160 genotypes were observed in the 9 STR loci, respectively. The heterozygosity was 0. 824-0. 884, the discrimination power （DP） was 0. 925-0. 969 and the polymorphism information content （PIC） was 0. 77-0. 86, respectively. The distribution met the Hardy-Weinberg equilibrium （P〉0.05）. The total discrimination power was 1. 00 ×10^-13 , the combined probability of exclusion for trio paternity testing was 0. 999989488. The combined probability of exclusion for duo-paternity testing was 0. 873436. Conclusion The 9 identification and paternity testing. They can be used as testing or cases with mutation events. STR loci are powerful and reliable for personal supplementary loci in fatherless （motherless）