中文摘要：

目的：探讨负压封闭引流（VSD）联合氧气治疗压疮对创面组织细菌量的影响。方法选择压疮患者60例，随机分为两组，对照组采取VSD治疗，观察组采用VSD治疗为主，并辅以间断高浓度氧气治疗。对两组治疗前后的疗效及创面细菌量进行对比分析。结果观察组治疗后总有效率为83．33％，明显高于对照组的总有效率（53．33％），差异有统计学意义（P＜0．05）。两组患者在治疗前的创面组织细菌量差异无统计学意义（P＞0．05），观察组在治疗1、3、7、10d后创面组织细菌量均显著低于对照组，差异有统计学意义（P＜0．01）。结论VSD联合氧气治疗对压疮创面感染的防治效果良好。

英文摘要：

Objective To investigate the influence of vacuum sealing drainage（VSD ）combined with oxygen therapy for treating pressure ulcers on bacterial count .Methods 60 patients with pressure ulcer in our hospital were selected and randomly divided into two groups .The control group adopted the VSD therapy ,while the observation group received VSD combined with interrupted high concentration oxygen therapy .The treatment effects and bacteri‐al count of wound surface were comparatively analyzed .Results The total effective rate after treatment in the obser‐vation group was 83 .33% ,which was significantly higher than 53 .33% in the control group ,the difference was sta‐tistically significant（P〈 0 .05） .The bacterial count of wound surface before treatment had no statistical difference be‐tween the two groups（P〉0 .05） ,the bacterial count on 1 ,3 ,7 ,10 d of treatment in the observation group were sig‐nificantly lower than those in the control group ,the differences were statistically significant（P〈 0 .01） .Conclusion VSD combined with oxygen therapy has better effect for preventing wound infection of pressure ulcer .