中文摘要：

目的对小儿洗手液的抑菌效果和刺激性进行初步研究。方法采用牛津杯法考察艾叶、丁香、土茯苓、地肤子的抑菌活性。再按艾叶：丁香：土茯苓：地肤子比例为1∶1∶1∶1、2∶2∶1.5∶1、6∶5∶2∶2的比例,比较抑菌效果。取小鼠,按同体左右侧自身对比法,采用单次、多次给药皮肤刺激性试验。结果艾叶、丁香、土茯苓、地肤子对金黄色葡萄球菌、大肠埃希菌均有不同程度的抑制作用。当艾叶、丁香、土茯苓、地肤子的配比为2∶2∶1.5∶1时,抑菌效果最佳。小鼠皮肤均未出现红斑,红肿等异常。结论小儿洗手液中四种药配比为2∶2∶1.5∶1时,抑菌效果最佳且对皮肤没有刺激性。

英文摘要：

Objective： To observe the bacteriostatic effect and the thrill of the kids＇ hand washing. Method： Using the Oxford cup method to observe the antibacterial effect of the folium artemisiae argyi, clove, rhizoma smilacis glabrae and fructus koehiae, the folium artemisiae argyi, clove, rhizoma smilacis glabrae and fructus kochiae had three matching： 1： 1： 1： 1,2： 2： 1.5：1 and 6： 5： 2：2 to observe the antibacterial effection. The male mice used the method of one body contrasting, the irritation tests were divided into single application test and sequential application tests. Results： the folium artemisiae argyi, clove, rhizoma smilacis glabrae and fructus kochiae had different control to the Staphylococcus aureus, E. coli pin. When the matching of the folium artemisiae argyi, clove, rhizoma smilacis gla- brae and fructus kochiae was 2： 2： 1.5：1 ,it was best to bacteriostat. The skin of these male mice no red spot and swollen. Conclusion： When the matching of these was 2：2： 1.5： 1, it was best to bacteriostat and no irritation to the skin.