中文摘要：

以便在 ryanodine 受体(RyR ) 上与新行动模式发现新奇杀虫药剂，一系列新奇酞酸酸 diamide 衍生物被设计并且综合。所有混合物被 1H NMR 系列和 HRMS 描绘。生物活动评价的初步的结果显示一些标题混合物对 Mythimna separata， Spodoptera exigua，和 Plutella xylostella 展出了优秀杀虫的活动。标题混合物 3-nitro-N-cyclopropyl-N-[2-methyl-4-(perfluoropropan-2-yl ) 苯基] phthalamide (4a ) 比控制(chlorantraniliprole ) 对有菱形斑纹的蛾是更有效的。从 Spodoptera exigua 的神经原的细胞内部的钙上的一些标题混合物的效果证明标题混合物是 RyR 使活跃之物。

英文摘要：

In order to discover novel insecticides with the new action mode on ryanodine receptor （RyR）, a series of novel phthalic acid diamide derivatives were designed and synthesized. All compounds were characterized by 1H NMR spectra and HRMS. The preliminary results of biological activity assessment indicated that some title compounds exhibited excellent insecticidal activities against Mythimna separata, Spodoptera exigua, and Plutella xylostella. The title compound 3-nitro-N-cyclopropyl-N＇-[2-methyl-4-（perfluoropropan-2-yl）phenyl]phthalamidte （4a） was more efficient against diamondback moths than the control （chlorantraniliprole）. The effects of some title compounds on intracellular calcium of neurons from the Spodoptera exigua proved that the title compounds were RyR activators.