中文摘要：

目的：观察奥曲肽治疗放疗相关性腹泻的疗效。方法：2011年8月-2014年9月我院收治在放疗过程中出现Ⅱ-Ⅳ级腹泻的患者67例，Ⅱ-Ⅲ级患者应用奥曲肽100μg皮下注射，每天3次，Ⅳ级患者给予奥曲肽25μg/h，持续泵入，每天8-12h，观察腹泻的治疗效果。结果：奥曲肽治疗67例放疗相关性腹泻的治愈率为85.07%，治疗后患者Karnofsky体力状态（ KPS）评分明显提高，未见明显不良反应。结论：奥曲肽治疗放疗相关性腹泻，尤其对Ⅱ-Ⅲ级腹泻有较好的疗效，安全可靠，有效改善患者生存治疗，保障放疗顺利进行。

英文摘要：

Objective：To exPlore the efficacy of octreotide in the treatment of radiotheraPy-induced acute diar-rhea（ RID）. Methods：All 67 Patients with grade Ⅱ-Ⅳ diarrhea during celiac or Pelvic radiotheraPy were analyzed during August 2011 and SePtember 2014. The grade Ⅱ-Ⅲ Patients were given the subcutaneous injection of oct-reotide（100μg,tid）. The grade Ⅳ Patients were continuously infused with 25μg/h octreotide for 8 -12h/day. Re-sults：The overall resPonse rate was 85. 07%. After treatment,the KPS scores were significantly imProved. In addition, no obvious adverse reaction was found. Conclusion：The theraPeutic efficacy of octreotide in the treatment of RID was effective and safe,and dramatically imProved the quality of life of Patients.