中文摘要：

目的：分析新疆和田维吾尔族老年人群中慢性牙周炎患者及无牙牙合患者唾液中4种牙周致病菌（牙龈卟啉单胞菌Pg,福赛坦氏菌Tf,中间普氏菌Pi,具核梭杆菌Fn）的检出特征,并初步探讨其与维吾尔族老年人慢性牙周炎发病之间的关系。方法：符合纳入标准的维吾尔族老年患者107例,PCR扩增4种目的菌,所得结果与患者临床信息进行综合分析并以流行病学方法进行描述。结果：唾液中各细菌的检出情况分别是：Pg菌（37例34.6%）,Tf菌（63例58.9%）,Pi菌（47例43.9%）,Fn菌（57例53.3%）。Pg女性检出率（26例48.15%）高于男性检出率（11例20.75%）,Fn女性检出率（34例2.96%）高于男性检出率（23例43.40%）,均有统计学差异（P〈0.05）。Tf男性女性检出率分别为（35例55.56%）和（28例51.85%）,Pi男性女性检出率分别为（22例41.51%）和（25例46.30%）,无统计学差异。Pg、Tf、Pi和Fn在教育程度、是否吸烟的检出率均无统计学差异,不刷牙和刷牙组均有统计学差异（P〈0.05）;CAL≥5mm组的Pg、Tf、Pi和Fn的检出率均高于CAL2-5mm组,有计学差异（P〈0.05）。有无牙牙合老人唾液中Pg、Tf、Pi和Fn检出率均无统计学差异。结论：新疆和田维吾尔族老年慢性牙周炎患者中优势牙周致病菌为TF,其次为Fn;在一定程度上促进了牙周炎的发展。

英文摘要：

Objective： To analyze the positive rate and dominant bacteria of four periodontal bacteria（Porphyromonas gingivalis Pg, Tannerella forsythia Tf, Prevotella intermedia Pi, Fusobacterium nucleatum Fn） in saliva among aged patients in Xinjiang Uygur who suffered chronic periodontitis and edentulousness.and to explore its relationship with the elderly Uygur chronic periodontitis. Methods：In accordance with the inclusion criteria of the Uygur elderly patients were107 cases and using PCR amplified 4 kinds of target bacteria. The results and the patient＇s clinical information were comprehensive analyzed and described by epidemiological methods. Results：Saliva in the bacterial detection were： PG（37 cases of 34.6%） bacteria, TF 63 cases（58.9%） bacteria, PI 47 cases（43.9%） bacteria, FN bacteria（57 cases53.3%）.Pg female detection rate（26 cases 48.15%） is higher than the male detection rate（11 cases of 20.75%）, FN female detection rate of 34 cases（2.96%） and high in male detection rate（23 cases of 43.40%）, there were significant difference among groups（P〈0.05）. However,the pattern breaks in Tf and Pi where the former shows men＇s detection rates 55.56%VS women＇s 51.85% whereas the latter with men＇s 41.51% VS women＇s 46.30%, no statistical difference. In addition, no statistical difference applies to the detection rates among various groups such as educational backgrounds, smoker and non-smoker. But statistical difference applies to the detection rate in brushing or not. Detection rates of periodontal pathogen vary between different CAL, and among them the group of CAL≥5mm shows the detection rates of Pg、Tf、Pi and Fn,which are higher than the corresponding CAL 2-5mm group（P〈0.05）. There is also no statistical difference to the detection rates of edentulous elderly＇s saliva. Conclusion：Tf is the dominant periodontal pathogen among aged Uygur in Hetian of Xinjiang chronic periodontitis patients, followed by Fn, and to a certain extent, promoted the devel