中文摘要：

目的：评价经皮椎体成形术（PVP）联合中药治疗骨质疏松性椎体压缩骨折（OVCF）的临床疗效和安全性。方法：计算机检索CNKI、万方、维普、CBM、PubMed和Medline数据库中公开发表的PVP联合中药治疗OVCF的随机对照试验（RCT）。由2名研究人员独立检索,筛选文献,并独立对纳入文献依据Cochrane系统评价方法学进行质量评价和数据提取。用RevMan 5.2软件进行Meta分析。结果：共纳入11个RCT,810例患者,其中治疗组429例,对照组381例。所有试验质量普遍不够高,未发现双盲试验。Meta分析结果显示,PVP联合中药与单纯PVP治疗OVCF相比,其总有效率、无效率和骨密度的影响差异有统计学意义（P〈0.00001）。结论：PVP联合中药可优势互补,其治疗OVCF较单纯PVP治疗更能提高临床疗效,减少不良反应的发生,是一种有希望的治疗选择,但仍需低风险、高质量的临床试验研究进一步加以验证。

英文摘要：

Objective： To evaluate clinical efficacy and safety of PVP combined with TCM for osteoporotic vertebral compression fractures（OVCF）. Methods： The randomized controlled trails on PVP combined with TCM for OVCF were searched and collected by the following databases such as CNKI, WANFANG, VIP, CBM, PubMed and Medline. Two researchers performed the literature searching and screening, and assessment of methodological quality and data extraction were performed independently. The methodological quality was assessed by using the Cochrane system evaluation methodology. Meta-analysis was performed by using RevMan 5.2 software. Results： In a total of 11 RCT cases, 810 patients（429 patients in treatment group, 381 patients in control group） were identii ed. All trials were not qualii ed in methodology, none of them was doubleblinded trials. Compared with the treatment with PVP, Meta-analysis results indicated that the inl uence of total clinical effective rate, inei ciency rate and bone mineral density had statistical signii cance in PVP combined with TCM treatment（P〈0.00001）. Conclusion： Compared with the treatment of PVP, PVP combined with TCM treatment has complementary advantages, which could improve the clinical curative effect and reduce the occurrence of adverse events. It will be a promising treatment option. But it still needs a low risk and high quality clinical trials to verify.