微小RNA(microRNAs,miRNAs)是一类参与基因转录后水平调控的小分子非编码RNA,广泛参与肿瘤发生发展等过程的调节。循环miRNAs是在外周血中发现的miRNAs,新近研究资料显示,循环miRNAs作为一种新型生物标志物可能在肺癌的诊断、疗效评估和预后判断中有着重要的作用和价值。
MicroRNAs (mic roRNAs, miRNA s) are a species of small non - coding single stranded RNA in regula-ting gene transcript ion level after participation, widely involved in the regulation of tumor occurrence and development. Circulating miRNAs are found in the peripheral blood,many recent studies have shown that circula ting miRNAs as new clinical biomarkers are important for the diagnosis, therapeutic effect and prognosis of lung cancer.