中文摘要：

目的：观察不同组的心电图及心肌酶谱,比较哪种穴位配伍对抗心肌缺血的作用更明显。方法：将经心电图筛查无异常的SPF级雄性Wistar大鼠随机分为4组,每组各10只：正常组（A）、模型组（B）、标本配穴防治组（C）、远近配穴对照组（D）。采用连续7 d盐酸异丙肾上腺素（ISO）皮下注射的方法造模。标本配穴防治组和远近配穴对照组,在造模前分别予以双内关、双足三里、关元穴,和双内关、膻中穴电针治疗10 min,1次/d,治疗持续21 d。实验结束后检测各组心电图和心肌酶谱（CK、CK-MB、AST、LDH）。结果：①模型组心电图S-T段显著提高;标本配穴防治组心电图S-T段提高幅度明显下降,明显低于模型组和远近配穴对照组（P〈0.05）。②标本配穴组的心肌酶CK、CK-MB、AST、LDH的活性显著降低,明显低于对照组和模型组（P〈0.05）。结论：标本配穴电针预处理明显抑制心肌缺血所致的ST段上抬和心肌酶活性的升高,优于常规配穴,能有效对抗心肌缺血。

英文摘要：

Objective： To observe ECG and myocardial in different groups,and compare which combined acupoints are better to against myocardial ischemia. Methods： 40 SPF Wistar rats without heart disease were randomized into four groups,each group with10 rats： normal group（ A）,model group（ B）,Biao and Ben pretreatment group（ C）,far and near control group（ D）. The rat model of myocardial ischemia was established by injecting ISO for 7 days. Before making the model,A and B was applied respectively to double＂Zusanli＂（ ST36）,＂Neiguan＂（ PC6）,＂Guanyuan＂（ RN4） acupoints,and double＂Neiguan＂（ PC6）,＂Danzhong＂（ RN17）acupoints,both with electric acupuncture for 10 min,once a day. At the end of the experiment,test ECG and myocardial enzyme（ CK,CK-MB,AST,LDH）. Results： ①ECG： S-T level of B was raised; S-T level of C was lower than that of B and D（ P〈0. 05）. ②Myocardial enzyme： CK,CK-MB,AST and LDH of C all were lower than that of B and D（ P〈0. 05）. Conclusion： The pretreatment with electric acupuncture of combined Biao and Ben acupoints could obviously reduce the S-T level and the activity of myocardial enzyme from myocardial ischemia,which is better than common combined acupoints and could protect myocardial cells from ischemia injury.