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许莫氏结节在腰腿痛患者中的分布特点及与腰椎间盘退变的相关性分析
  • ISSN号:0253-2352
  • 期刊名称:《中华骨科杂志》
  • 时间:0
  • 分类:R681.53[医药卫生—骨科学;医药卫生—临床医学;医药卫生—外科学]
  • 作者机构:[1]浙江大学医学院附属邵逸夫医院骨科,杭州310016
  • 相关基金:国家自然科学基金(81271971,81301587),浙江省自然科学基金(Y2110372,LQ13H060002),浙江省卫生高层次创新人才培养工程项目,浙江省重大科技专项重点社会发展项目(2009C0304-1)
中文摘要:

目的探讨许莫氏结节在腰腿痛患者中的分布特点,并分析许莫氏结节与腰椎间盘退变的相关性。方法选择2012年因腰腿痛行腰椎MR检查的患者1024例,男448例,女576例;年龄22-90岁,平均(54.3±12.7)岁。分析许莫氏结节在腰椎节段、年龄、性别、椎间盘退变分类及分级中的分布特点和相关因素。结果1024例5120个腰椎节段中,295例(28.8%)532个终板(5.2%)发生许莫氏结节,302个位于头侧终板,230个位于尾侧终板。节段分布以L1.2最为常见(29.1%),其次为L3.4(23.7%)和L2.2(21.1%)。许莫氏结节发生率基本上呈随年龄增加而增高的趋势,但与性别、体重、身高、体重指数无关。许莫氏结节在腰椎间盘膨出、脱出,Modie改变,腰椎滑脱和骨赘形成患者中发生率较高。发生许莫氏结节和不发生许莫氏结节椎间盘退变分级的分布差异有统计学意义,发生许莫氏结节组的退变分级明显高于不发生许莫氏结节组。许莫氏结节的数量、大小和体积均与对应椎间盘的退变分级相关。根据MRI信号类型将发生许莫氏结节分为“急性炎症水肿期”组和“非急性期”组,两组所对应椎间盘退变分级的分布差异有统计学意义,“非急性期”组对应的椎间盘退变程度更严重。结论在腰腿痛患者中,许莫氏结节好发于上腰椎,多见于头侧终板,与年龄、椎间盘退变分级存在相关性。许莫氏结节的数量、大小、体积、MRI信号类型影响其与椎间盘退变的相关性。

英文摘要:

Objective To evaluate the distribution of Schmorl's nodes (SN) in patients with low back pain or radiculopa-thy, and to analyze the correlation between SN and degeneration of lumbar intervertebral discs. Methods In 2012, 1024 pa-tients with low back pain or sciatica were examined by magnetic resonance (MR) scan and plain film. There were 448 males and 576 females, with an average age of (54.3 ± 12.7) years (range, 22-90). The features distribution of SN in lumbar endplate on age, sex, segment and the type and grade of intervertebral disc degeneration were analyzed retrospectively. Results Among 5120 lumbar intervertebral segments of the 1024 patients, 295 (28.8%) cases and 532 (5.2%) endplates were involved with SN, 302 located in the cranial and 230 in the caudal endplate. According to percent prevalence per lumbar segment, L1.2 was the most common level (29.1%), followed by L3.4 (23.7%) and L2.3 (21.1%). The incidence of SN was positively correlated with elder age, but not with sex, body weight, height, or body mass index. SN occurred more often in bulging, extrusion, Modic changes, spondylolisthesis and osteophyte comparing with normal disc or protrusion or high intensity zone. The distributions of the grade of intervertebral disc degeneration were significantly different between groups with and without adjacent SN. Intervertebral discs with adjacent SN were more degenerated than those without adjacent SN. The number, size and volume of SN were associated with the degrade of intervertebral discs degeneration. SN was divided into two types, i.e., "acute edematous" SN and "non-acute" SN, according to the signal type on T~- and T2-weighted MR images, and the degeneration of the corresponding intervertebral discs was more severe in the latter than the former group. Conclusion SN occurred more often in the upper lumbar spine and cranial endplate in patients with low back pain or radiculopathy. SN were correlated with elder age and the degeneration of lum- bar intervert

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期刊信息
  • 《中华骨科杂志》
  • 中国科技核心期刊
  • 主管单位:中国科学技术协会
  • 主办单位:中华医学会
  • 主编:
  • 地址:天津市河西区解放南路406号
  • 邮编:300211
  • 邮箱:gktougao@126.com
  • 电话:022-28334734 28278929
  • 国际标准刊号:ISSN:0253-2352
  • 国内统一刊号:ISSN:12-1113/R
  • 邮发代号:6-17
  • 获奖情况:
  • 中国期刊方阵“双效”期刊
  • 国内外数据库收录:
  • 俄罗斯文摘杂志,美国化学文摘(网络版),英国农业与生物科学研究中心文摘,波兰哥白尼索引,美国剑桥科学文摘,日本日本科学技术振兴机构数据库,中国中国科技核心期刊,中国北大核心期刊(2004版),中国北大核心期刊(2008版),中国北大核心期刊(2011版),中国北大核心期刊(2014版),中国北大核心期刊(2000版)
  • 被引量:67445