中文摘要：

目的应用三维斑点追踪成像技术（three-dimensional speckle tracking imaging，3D-STI）分析冠状动脉造影正常者左心室短轴应变，探讨用3D-STl分析左心室心肌形变特征的可行性。方法收集北京安贞医院行冠状动脉造影检查冠状动脉正常者24例，行Toshiba Artida彩色多普勒超声检查，应用3D-STI在线分析软件分析左心室短轴应变参数，其中包括径向峰值应变和圆周峰值应变。结果①左心室收缩期整体径向应变为30．91％±16．19％。左心室心尖段收缩期峰值径向应变较小，中间段较大。心尖段各室壁径向峰值应变与基底段径向峰值应变、中间段径向峰值应变有统计学差异（P〈0．05或P〈0．01），同水平不同室壁节段径向峰值应变差异无统计学意义（P〉0．05）。②左心室短轴收缩期整体圆周应变为-29．47％±12．46％。左心室收缩期峰值圆周应变从基底段至心尖段渐增大。除前室间隔外的其他室壁心尖段与基底段、中间段比较，收缩期峰值圆周应变差异均有统计学意义（P〈0．05）。结论3D-STI可以通过短轴应变评估冠脉造影正常者左心室心肌形变的特征。

英文摘要：

Objective To investigate biomechanical characteristics of left ventricular myocardial deformation in short axis by evaluating short axis systolic strain of left ventricle in healthy people with normal coronary angiography by using three-dimensional speckle tracking imaging （3D-STI）. Methods There were 24 patients （14 males and 10 females） with normal coronary enrolled in the study. Toshiba Artida color Doppler was used to collect and store standard apical four chamber view of left ventricular full volume images. And 3D- STI online analysis software was used to analyze the group, including： global radial strain （GRS）, global circumferential strain （GCS）. Results ① Left ventricular GRS was 30.91% ＋ 16. 19%. GRS of mitral valve level,papillary muscle level were statistically significant compared with GRS of apex level （P〈0.05 or P 〈0.01）. There was no difference in GRS among the same level of the different walls （P 〉0.05）. ② Left ventricular GCS was - 29.47% ＋ 12.46% . Left ventricular GCS increased gradually from the base level to the apex level. Except septal anterior ventricle, GCS of mitral valvelevel,papillary muscle level were statistically significant compared with GCS of the apex level （P 〈 0.05）. Conclusions This study revealed the characteristics of GCS and GRS of the healthy people.