对羊踯躅植物花蕾的化学成分进行研究,应用多种色谱技术进行分离纯化、波谱技术鉴定其结构。从羊踯躅花蕾中分离并鉴定了15个化合物,分别为2E,4Z-脱落酸(1),2α-羟基齐墩果酸(2),齐墩果酸(3),积雪草酸(4),苯甲基糖苷(5),邻苯二甲酸二丁酯(6),β-谷甾醇(7),牡荆素(8),槲皮素(9),硬脂酸(10),rhodomollein Ⅰ(11),rhodojaponin Ⅵ(12),rhodomollein Ⅺ(13),rhodojaponin Ⅱ(14),kalmanol(15)。其中,化合物1 10为首次从羊踯躅植物中得到。
The aim of current study was to investigate the chemical constituents from the flowers of Rhododendron molle G. Don. The isolation and purification of components were achieved by a series of chromatography including silica gel, Sephadex LH-20, and reversed-phase HPLC. Their structures were identified based on 1D, 2D NMR, and mass spectral analysis. Fifteen known compounds were isolated and their structures were identified as 2E,4Z-abscisic acid(1), 2α-hydroxy-oleanolic acid(2), oleanic acid(3), asiatic acid(4), benzyl glucoside(5), dibutyl phthalate(6), β-sitosterol(7), vitexin(8), quercetin(9), steraric acid(10), rhodomollein I(11), rhodojaponin VI(12), rhodomollein XI(13), rhodojaponin II(14), kalmanol(15). Compounds 1–10 were isolated from Rhododendron molle for the first time.