对全球6个国家的HIV/AIDS流行趋势进行预测,并给出资源分配的方案.首先利用基本离散时间动力学多分组模型,得到了6国2006—2050年HIV/AIDS感染者人数的变化.然后考虑ARV药物和HIV/AIDS疫苗的使用,修正基本模型,对6国2010—2050年HIV/AIDS感染者人数进行了估计.再考虑ARV药物抗药性的影响,完善修正模型,预测了美国2010~2050年HIV/AIDS感染者人数变化.最后基于线性支出系统效用函数,建立一个非线性规划模型来对6个国家分配资源.
Future HIV/AIDS prevalence trend is predicted in six countries, and a fund allocation model for six countries is given. A basic discrete-time dynamic multi-group model is used to calculate the number of HIV/AIDS infections from 2006 to 2050 for six countries. Then two new modified multi-group models are established respectively by considering the effect of antiretroviral (ARV) drug therapy and/or a preventative HIV/AIDS vaccine, and by considering ARV-resistant disease strains. Therefore, the number of HIV/AIDS infections from 2010 to 2050 for six countries is estimated respectively. Finally, a nonlinear programming model is proposed for fund allocation for the six countries.