从磁镊实验和模拟角度研究了处于谐振势阱中的布朗运动.利用实验和模拟的结果验证了理论.然后通过理论与实验的对照,对磁镊实验中DNA分子的持久长度大小对小球位移分布的影响,以及磁镊实验中的测力误差作了相关分析.分析指出:持久长度的变化对沿DNA链方向上的布朗运动影响更大;小的外力作用下力的测量会出现较大误差.
The Brownian motion in a harmonic trap is studied by magnetic tweezers experiment and computer simulation. The results of the experiment and simulation validate the theory. Then the theory is used to analyze the experimental results including the effect of persistent length of DNA on the displacement distribution of the bead and the error in force measurements. It can be concluded that the variation of the persistent length affects more the Brownian motion along the DNA chain than in the other direction; under a small force, a considerable error of the force measurement will occur.