中文摘要：

目的研究PET-CT诊断早期子宫颈癌淋巴结转移的敏感性和特异性。方法回顾性分析2007年10月至2012年10月在中国医科大学附属盛京医院术前行PET-CT检查的所有Ⅰa-Ⅱa期子宫颈癌患者资料。并将淋巴结病理结果与区域淋巴结的组织径线相联系并比较。结果共有102例患者纳入本研究。28．4％的患者存在盆腔淋巴结转移。PET-CT检测盆腔淋巴结转移的敏感度、特异度、阳性预测值及阴性预测值为分别为37．9％、91．8％、66．7％及79．8％。11．1％的患者存在腹主动脉旁淋巴结转移。PET-CT检测腹主动脉旁淋巴结转移的敏感度、特异度、阳性预测值及阴性预测值为分别为40．0％、97．5％、66．7％及92．9％。真阳性和假阴性2组淋巴结的平均径线无统计学差异（P〉0．05）。结论PET—CT诊断早期子宫颈癌淋巴结转移的敏感性较低，特异性较高。

英文摘要：

Objective To determine the sensitivity and specificity of PET in diagnosis of lymph node metastasis in patients with early-stage cervical carcinoma. Methods Clinical data of all patients with stage I A- II A cervical carcinoma who underwent PET before surgery be- tween Oct 2007 and Oct 2012 were retrospectively reviewed. The histologic size of the regional lymph nodes and lymph node pathology was compared and correlated. Results Totally 102 patients were recruited for the current study. Pelvic lymph node metastases were present in 28.4% of the patients and detected by PET with a sensitivity of 37.9%,a specificity of 91.8%,a positive predictive value （PPV） of 66.7%, and a negative predictive value （NPV） of 79.8%. Paraaortic lymph node disease was present in 11.1% of patients and detected by PET with a sensitivity of 40.0%,a specificity of 97.5% ,a PPV of 66.7% ,and an NPV of 92.9%. There was no statistical difference of mean histologic size of the involved lymph nodes between the PET-positive pelvic lymph nodes and the PET-negative pelvic lymph nodes （ 15.6 mm vs. 13.7 mm; P = 0.256）. Conclusion PET-CT has a low sensitivity but a high specificity for diagnosis of lymph node metastasis in patients with early-stage cervical carcinoma.