中文摘要：

目的 观察穴位贴敷对哮喘大鼠嗜酸粒细胞及肺组织超微结构的影响.方法 参考Palmans方法建立哮喘大鼠模型,观察予穴位贴敷治疗后大鼠全血白细胞数量和嗜酸粒细胞值以及肺组织超微结构变化.结果 模型组大鼠全血白细胞和嗜酸粒细胞较正常组明显增加,各治疗组大鼠全血白细胞和嗜酸粒细胞较模型组明显减少.穴位贴敷可有效改善哮喘大鼠肺泡上皮细胞结构.结论 穴位贴敷可以减少大鼠全血白细胞和嗜酸粒细胞数量,减轻哮喘大鼠肺组织炎症细胞浸润及肺泡上皮细胞坏死,从而发挥治疗哮喘的作用.

英文摘要：

Objective To observe the effect of acupoint sticking therapy on eosinophils infiltration and the lung tissue ultrastructure of asthmatic rats. Methods Using rat model of asthma which is established following Palmans＇ method, we observed the effect of acupoint sticking therapy on the whole blood leukocyte count, eosinophils and ultrastructural changes in lung tissue. Results The whole blood leukoeytes and eosinophils counts were significantly increased in asthma model group compared with the sham group. After treatment with acupoint sticking therapy, the whole blood leukocytes and eosino- phils counts were significantly decreased and the ultrastructure of alveolar epithelial cells was also obvi- ously improved in asthma rats. Conclusion Acupoint sticking therapy can reduce the whole blood leukocytes and eosinophils counts and alleviate inflammatory cell infiltration and alveolar epithelial cell necrosis in the lung of asthmatic rats to treat asthma.