中文摘要：

核转录因子Nrf2信号通路是调控细胞对抗外来异物和氧化损伤的关键通路，已经明确其在细胞凋亡中发挥十分重要的作用。本文从Nrf2信号通路对细胞凋亡的保护作用、与凋亡相关蛋白之间的相互作用、以及促进肿瘤细胞凋亡和增强肿瘤细胞耐药性的双重作用等方面，就细胞凋亡与Nrf2信号通路关系的相关研究进展进行综述。

英文摘要：

The nuclear transcription factor Nrf2 signaling pathway is the key pathway responsible for cell defense against exogenous foreign bodies and oxidative stress. Nrf2 has proven to play an important role in apoptosis. Based on the protective effect on apoptosis from the Nrf2 signaling pathway, the interaction of Nrf2 and apoptosis-related protein and the dual role of Nrf2 promote tumor cell apoptosis and enhance tumor cell resistance, we reviewed on research advance of apoptosis and Nrf2 signaling pathway.