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The hemocompatibility and the reabsorption function of TiO2 nanotubes biomembranes
  • ISSN号:1001-6538
  • 期刊名称:Chinese Science Bulletin
  • 时间:2012.6.6
  • 页码:2022-2028
  • 分类:Q73[生物学—分子生物学] TB383[一般工业技术—材料科学与工程]
  • 作者机构:[1]State Key Laboratory of Materials Processing and Die & Mould Technology, Huazhong University of Science and Technology, Wuhan 430074, China, [2]School of Life Science and Technology, Huazhong University of Science and Technology, Wuhan 430074, China
  • 相关基金:This work was co-financed by the National Natural Science Foundation of China (21173090, 30970717 and 20873048), the Specialized Research Fund for the Doctoral Program of Higher Education (200804871011), and the Fundamental Research Funds for the Central Universities, HUST (2010MS113). Technical assistance from the Analytical and Testing Center of HUST is also gratefully acknowledged.
  • 相关项目:TiO2纳米管阵列同轴异质结的调控制备、电荷传输机理及产氢特性研究
作者: 朱文|
中文摘要:

新奇高紧张的 TiO2 nanotubes 数组膜经由高度纯的钛陪衬的电气化学的阳极化被制作,无限制的 TiO2 nanotubes 数组膜被在 nanotubes 的底部蚀刻的 HF 气体获得。猪管状的上皮的房间(LLC-PK1 ) 和脉管的 endothelial 房间(ECV304 ) 与生理的功能通过一个混合培植方法和 TiO2 nanotubes biomembrane 材料在无限制的 TiO2 nanotubes 表面上被栽培成功地被生产。玻璃幻灯片,纯钛,没有房间的 TiO2 nanotubes 和有文化房间的 TiO2 nanotubes 的 Hemocompatibility 被血浆石灰化时间方法和钠的重吸收调查,钾被设计习俗的设备测量。结果证明有文化房间的 TiO2 nanotubes 数组膜的 hemocompatibility 比控制组优异,并且 biomembrane 有一个优秀重吸收函数。这证明 TiO2 nanotubes 数组膜有优秀生理的功能并且是为生物分离的理想的候选人材料。

英文摘要:

A novel high-intensity TiO2 nanotubes array membrane was fabricated via electrochemical anodization of highly pure titanium foil and an open-ended TiO2 nanotubes array membrane was obtained by HF gas etching at the bottom of the nanotubes. Pig tubular epithelial cells (LLC-PK1) and vascular endothelial cells (ECV304) were cultivated on the open-ended TiO2 nanotubes surface through a mixing implantation method and TiO2 nanotubes biomembrane materials with physiological function were successfully produced. Hemocompatibility of glass slides, pure titanium, TiO2 nanotubes without cells and TiO2 nanotubes with culture cells were investigated by the plasma recalcification time method and reabsorption of sodium and potassium were measured by custom-designed devices. The results show that the hemocompatibility of the TiO2 nanotubes array membrane with culture cells was superior to the control group, and the biomembrane has an excellent reabsorption function. This demonstrates that a TiO2 nanotubes array membrane has excellent physiological function and is an ideal candidate material for biological dialysis.

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