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Controlling the Release of bFGF from Silk Fibroin Membrane

ISSN号：0895-3988
期刊名称：Biomedical and Environmental Sciences
时间：2014.12
页码：973-977
分类：TS149[轻工技术与工程—纺织材料与纺织品设计;轻工技术与工程—纺织科学与工程] Q516[生物学—生物化学]
作者机构：[1]Jiangsu Key Laboratory of Neuroregeneration, Nantong University, Nantong 226001, Jiangsu, China, [2]College of Chemistry and Chemical Engineering, Nantong University, Nantong 226001, Jiangsu, China, [3]The Neural Regeneration Co-innovation Center of Jiangsu Province, Nantong University, Nantong 226001, Jiangsu, China
相关基金：This work was supported by the National High Technology Research and Development Program of China （2012AA020502）, National Natural Science Foundation of China （81171457 and 813716874 the Priority of Academic Program Development of Jiangsu Higher Education Institutions （PAPD）, and Natural Science Foundation of Jiangsu Province of China （BK20130390）.
相关项目：具有轴向排列结构的人工神经导管的构建及机制研究

作者： Yaling WANG|Jing ZHAO|Luzhong ZHANG|Yumin YANG|

关键词：丝素膜, BFGF, 神经营养因子, 控制, 丝素蛋白, 装载效率, 持续释放, 半衰期

中文摘要：

<正>Since neurotrophic factor is easy to degrade and aggregate,it usually has a short half-life in vitro.To overcome this shortage,neurotrophic factor has been combined with the silk fibroin(SF)membrane to realize less degradation,optimal loading efficiency,sustained release,and good adsorption.

英文摘要：

Since neurotrophic factor is easy to degrade and aggregate, it usually has a short half-life in vitro. To overcome this shortage, neurotrophic factor has been combined with the silk fibroin （SF） membrane to realize less degradation, optimal loading efficiency, sustained release, and good adsorption.

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