中文摘要：

目的：合成红景天苷类似物,并初步分析评价其抗氧化能力。方法：以O-乙酰基溴代葡萄糖、O-乙酰基溴代半乳糖为糖基供体,芳环不同取代的苯甲醇、苯乙醇为糖基配体通过Koenigs-Knorr法制备红景天苷类似物,并采用微孔板定量法分析测定其对2,2-二苯基苦基苯肼自由基（DPPH.）的清除能力。结果：合成了10个类似物糖苷,确定了其在清除DPPH.反应达到50%时的IC50（μmol/L）。结论：所合成类似物3-（3,4,5-三羟基苯基）丙基-β-D-葡萄糖苷和3-（3,4,5-三羟基苯基）丙基-β-D-半乳糖苷具有较好的抗氧化能力,其IC50分别为36.7μmol/L和39.7μmol/L,优于阳性对照维生素CIC50（54.6μmol/L）。

英文摘要：

Objective： To synthesize salidroside analogues and evaluate its antioxidative capability tentatively.Method： The synthesis was conducted through Koenigs-Knorr method,O-acetobrome-sugar（glucose and galactose） as glycon donor and different substituted benzyl alcohol and phenylethyl alcohol as aglycone,and microplate quantification（MQ） of 2,2-diphenyl-1-picrylhydrazyl（DPPH·） was used to evaluate its scavenging capability.Results： Ten salidroside analogues were synthesised,the IC50（μmol/L） of which were afforded.Conclusion： Compounds 3-（3,4,5-Trihydroxyphenyl） propyl β-D-glucopyranoside and 3-（3,4,5-Trihydroxyphenyl） propyl β-D-galactopyranoside displayed good antioxidant capacity,IC50 being 36.7 μmol/L and 39.7 μmol/L,respectively,superior to VCIC50（54.6 μmol/L） in the positive control.