背景 Polycystic 卵巢症候群( PCOS )被认为是在在遗体 unclear.We 试图在社区和医院病人 populations.Methods 女人与 PCOS 分析反常月经周期和他们的协会的特征与的 PCOS 的病原学的一个反常月经周期的繁殖 age.The 参与的女人的最普通的内分泌的混乱在从 reproductiv 获得的北京和 506 个门诊病人的社区从 2111 个永久女居民识别的 PCOS 21 天;21-34 天;35-60 天;并且在每个组的 60 days.Women 用一张问询表被会见包括年龄估计因素,月经初潮的年龄,月经周期历史,相关家庭历史,并且修改了 score.All 女人收到了的 Ferriman-Gallwey ( mF-G ) transvaginal 超声扫描和为 0.05 的二尾巴的 P 价值在社区人口被认为 significant.Results 的内分泌的 evaluation.A 拿的有的 fasting 血样品,反常月经周期的流行是27.19%( 574/2111 ) PCOS 在的 .The 流行
Background Polycystic ovary syndrome (PCOS) is considered to be the most common endocrine disorder in women of reproductive age.The involvement of an abnormal menstrual cycle in the etiology of PCOS remains unclear.We aimed to analyze the characteristics of abnormal menstrual cycles and their association with PCOS in community and hospital patient populations.Methods Women with PCOS identified from 2111 permanent female residents in the community of Beijing and 506 outpatients obtained from the reproductive clinic of Peking University Third Hospital were recruited for this study,comprising the PCOS community group and the PCOS hospital group, respectively.Each group was further divided into four subgroups according to the length of menstrual cycles: 〈21 days; 21-34 days; 35-60 days; and 〉60 days.Women in each group were interviewed using a questionnaire to assess factors including age, age of menarche, menstrual cycle history, related family history, and modified Ferriman-Gallwey (mF-G) score.All women received transvaginal ultrasound scan and had fasting blood samples taken for endocrine evaluation.A two-tailed P value of 〈0.05 was considered significant.Results In the community population, the prevalence of abnormal menstrual cycle was 27.19% (574/2111).The prevalence of PCOS in the community was 6.11% (129/2111) according to Rotterdam criteria.In the community group,the most common menstrual cycle length was 35-60 days, whereas for the hospital group, it was 〉60 days.In both the community and hospital groups, the most common phenotype of PCOS was that of Oligo/amenorrhea+PCO+hyperandrogenism (HA) (O+P+H) (P=0.000).With increasing cycle length of 35-60 days to 〉60 days, the percentages of Oligo/amenorrhea+PCO (O+P) and O+P+H were found to significantly decrease in the community group and significantly increase in the hospital group (P=0.000 for each).In the hospital group, as the menstrual cycle length increased from 35-60 days to 〉60 days, the r