中文摘要：

阿尔茨海默病（AD）是一种脑神经退变性疾病。在AD发病机理方面，脑中β-淀粉样斑块的形成是一个主要因素，β-淀粉样斑块显像剂对于AD的早期诊断具有重要的临床意义。结合本实验室工作，本文介绍了β-淀粉样斑块显像剂的发展过程和目前国内外的最新进展，并对β-淀粉样斑块显像剂的未来发展方向作了展望。

英文摘要：

Alzheimer＇s disease （AD） is a kind of degenerative neurodisease. The formation of β-amyloid plaques in brain is one of the main factors in developing of AD. Imaging agents for β-amyloid plaques are of great significance to early diagnosis of AD. The recent advances in imaging agents for β-amyloid plaques domestic and abroad as well as work in my laboratory are reviewed in this paper. The trend for developing β-amyloid plaques imaging agents is also discussed.