中文摘要：

［1］郭晓东 杜靖远 郑启新等.组织工程学技术修复关节软骨缺损研究进展.国外医学生物医学工程分册 2000 23(6):330 ［2］郭晓东 杜靖远 郑启新等.骨关节炎基因治疗进展.国外医学老年医学分册 2001 22(1):29 ［3］Grande D Breitbart A Mason J et al.Cartilage tissue engineering:current limitations and solutions.Clin Orthop 1999 367S:S176 ［4］Brittberg M Lindahl A Nilsson A et al.Treatment of deep cartilage defects in the knee with autologous chondrocyte transplantation.N Engl J Med 1994 331:889 ［5］Reddi A.Morphogenesis and tissue engineering of bone and cartilage:inductive signals stem cells and biomimetic biomaterials.Tissue Eng 2000 6(4) :351 ［6］Freed L Martin I Vunjak-Novakovic G.Frontiers in tissue engineering:in vitro modulation of chondrogene sis.Clin Orthop 1999 367S:S46 ［7］Evans C Ghivizzani S Smith P et al.Using gene therapy to protect and restore cartilage.Clin Orthop 2000 379 (Suppl) :S214 ［8］Fernandes J Martel-Pelletier J Pelletier J.Gene therapy for osteoarthritis:new perspectives for the twentyfirst century.Clin Orthop 2000 379(Suppl):S262 ［9］Mason J M Breitbart A S Barcia M et al.Cartilage and bone regeneration using gene-enhanced tissue engineering.Clin Orthop 2000 379 (Suppl):S171 ［10］郭晓东 杜靖远 郑启新等.分子生物学在组织工程学研究中的应用前景.中华实验外科杂志 2001 18(3):283 ［11］郭晓东 全大萍.组织工程与生物材料.见:生物医用材料导论.李世普主编.武汉:武汉工业大学出版社 2000.302 ［12］Liu Y Zheng Q X Du J Y et al.Cloning and expression of rat transforming growth factorβ1 cDNA in osteoblasts.J Tongji Med Univ 2000 20:63 ［13］Johnstone B Yoo J.Autologous mesenchymal progenitol cells in articular cartilage repair.Clin Orthop 1999 367S:S156 ［14］Yoo J Mandell I Angele P et al.Chondrogenitor cells and gene therapy.Clin Orthop 2000 379 (Suppl):S164 ［15］Caplan A I.Mesenchymal stem cells and gene therapy.Clin Orthop 2