中文摘要：

目的观察PCI术前给予负荷剂量瑞舒伐他汀对ACS患者LVEF的影响。方法将实行PCI的35例ACS患者随机分为负荷剂量组和对照组，负荷剂量组（n=20）术前给予负荷剂量瑞舒伐他汀20mg，术后每晚睡前10mg维持；对照组（n=15）只是术后每晚睡前10mg雏持。所有患者术后i个月行超声心动图检查，了解LVEF变化。结果负荷剂量组术后1个月LVEF较对照组提高更明显，差异有统计学意义（P〈0．05）。结论PCI术前应用负荷剂量瑞舒伐他汀可以提高ACS患者的LVEF，改善心功能。

英文摘要：

Objective To observe the effect of loading rosuvastatain on the left ventricle eject fraction （LVEF） before percutaneous coronary intervention （PCI） in patients with acute coronary syndrome （ACS）. Methods A total of 35 ACS patients were divided randomly into two groups. 20 patients （loading group） were gived 20 mg loading rosuvas- tatain before PCI by per os, and continued taking 10 mg rosuvastatain every night after PCI; 15 patients （control group） taked lOmg rosuvastatain every night after PCI. All patients were checked the left ventricle eject fraction by ultrasonic cardiogram after PCI of one month. Results Compared control group, the LYEF was improved more in load- ing group. It had statistical significance （P 〈 0.05）. Conclusion It might improve the left ventricle eject fraction before percutaneous coronary intervention by giving loading rosuvastatain in patients with acute coronary syndrome.