中文摘要：

目的：研究急性冠状动脉综合征（ACS）患者血清淀粉样蛋白A（SAA）水平的变化，探讨其作为易损斑块的检测指标的可能性。方法：设ACS组29例，慢性稳定型心绞痛（SAP）组28例，对照组31例。酶联免疫吸附测定法（ELIsA）测定高敏C反应蛋白（hsCRP）、白细胞介素-6（IL-6）、肿瘤坏死因子α（TNF—α）及SAA的表达比较。结果：ACS组血清hs—CRP、IL-6、TNF-α及SAA水平明显高于SAP组及对照组（P〈0．01）；SAP组4种炎症标记物与对照组比较差异无统计学意义（P〉0．05）。结论：ACS患者SAA水平显著增高，对ACS的预测可能有重要的价值。

英文摘要：

Objective：To explore the effect of serum amyloid A （SAA） protein on patients with acute coronary syndrome （ACS）. Method： There were three groups including ACS group （n = 29 ）, chronic stable angina pectoris （SAP） group （ n = 28） and control group （n= 31 ）. High sensitivity C-reactive protein （ hs-CRP）, interleukin-6 （IL-6）, tumor necrosis factor-alpha （TNF-α） and SAA protein were measured with enzymeqinked immunosorbent assay. Resalt：Hs-CRP, IL 6, TNF-α and SAA in patients with ACS were significantly higher than those in SAP and control group （P〈0.01）. These 4 kinds of inflammatory markers had no obvious differences between SAP and control group （P〉0.05）. Conclusion： SAA increases in patients with ACS and may be a valuable marker for predicting the severity of ACS.