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Neuroprotective effect of ethyl acetate extract from gastrodia elataagainst transient focal cerebral ischemia in rats induced by middlecerebral artery occlusion

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分类：R2[医药卫生—中医学]
作者机构：[1]the Key Modern Research Laboratory forEthno-pharmacognosy of Yunnan Higher School, YunnanUniversity of Traditional Chinese Medicine, Kunming650500, China, [2]the Department ofPharmacology, Yunnan University of Traditional ChineseMedicine, Kunming 650500, China, [3]Center for Neuron and Disease, Frontier Insti-tute of Science and Technology, Xi'an Jiaotong University,Xi'an 710054, China
相关基金：Supported by Natural Science Foundation of China (Anti-ischemic Brain Injury and Neuroprotection Mechanisms of Phenolic Compounds Distributed in Brain from Gastrodia,No.81160514);Yunnan Applied Basic Research Projects (Protective Effect and Mechanisms of 4-Methoxybenzyl from Gastrodia Elata on the Neurovascular Unit,No.2014FB153);Traditional Chinese Medicine Education Innovation Fund of Yunnan Baiyao-Yunnan University of TCM (The Regulation Role of Ethyl Acetate Extract from Gastrodia Elata on NO Pathway,No.YB2014J04)

作者： Duan Xiaohua[1], Wang Weili[2], Liu Xiaoqing[3], Yan Hanwen[2], Dai Rong[2], Lin Qing[1]

关键词： ETHYL, ACETATE, Gastrodia, Neuroprotec-tive, AGENTS, REPERFUSION, INJURY, Apoptosis

中文摘要：

OBJECTIVE： To investigate the protective effect ofneuroprotection against transient focal cerebralischemia of the extract from Tianma （Rhizoma Gas-trodiae） and the possible mechanisms underlyingthe action.METHODS： Cerebral ischemia-reperfusion injurywas induced through middle cerebral artery occlu-sion （MCAO）.

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