中文摘要：

调查是否的目的位于下面轮流出现的神经代表二 acupoint 联合(交流) 是一样。在这功能的磁性的回声成像的方法学习，痛觉缺失交流的二个集合被利用包括 Waiguan (TE5 ) 和为组 A，和 Neiguan 和为组 B 的 Taichong (LR3 )(PC6 ) 的 Qiuxu (GB40 ) ，它是通常在临床的治疗采用的大多数。每个组有 20 个健康题目。一个试验性的图案被建议，它由放松阶段的一个预先刺破的休息阶段，一个刺破的阶段和 needling 以后组成了。这个范例最佳地象刺激和休息时期的焦点一样模仿临床的协议。结果受到一般线性模型分析，连词分析和功能的连接分析。结果喙的前面的 cingulated 外皮在两个组从事针灸效果的创始的时期，并且它为下列休息时期为功能的连接分析被选择为种子区域。结果证明几个分享的大脑区域涉及两个组，特别地 insula，杏仁之类和视下丘。而且，重要差别在由二样品测试揭示了的以后的 cingulated 外皮被定位(P < 0.05，改正) 。另外的区域没显示出重要差别。这发现被二个组显著地被相关的空间关联分析进一步支持(r =0.51， P < 0.01 ) 。结论这初步的研究帮助我们当在交流上遵循临床的指南时，理解针灸的 neurophysiological 机制，以及提供一个重要机会为减少，或甚至阻止疼痛开发更好的治疗策略。

英文摘要：

Objective： To investigate whether the neural representations underlying alternating two acupoint combinations （ACs） are the same or not. Methods： In this functional magnetic resonance imaging study, two sets of analgesia ACs were utilized, including Waiguan （TE5） and Qiuxu （GB40） for Group A, and Neiguan （PC6） and Taichong （LR3） for Group B, which are the most commonly adopted in clinical treatment. Each group had 20 healthy subjects. An experinlental design was proposed, which consisted of a pre-needling resting phase, a needling phase and a post-needling resting phase. This paradigm optimally mimics the clinical protocol as well as focuses on both the stimulation and the resting periods. The results were subjected to general linear model analysis, conjunction analysis and the functional connectivity analysis. Results： The rostral anterior cingulated cortex was engaged in the initiative period of the acupuncture effect in both groups, and it was chosen as the seed region for the functional connectivity analysis for the following resting period. The results showed that several shared brain regions were involved in both groups, in particular the insula, amygdala and hypothalamus. Moreover, significant differences were located at the posterior cingulated cortex as revealed by a two sample t-test （P〈0.05, corrected）. Other regions showed no significant differences. This finding was further supported by the spatial correlation analysis that the two groups were significantly correlated （r=0.51, P〈0.01）. Conclusion： This preliminary research helps us understand the neurophysiological mechanisms of acupuncture when following clinical guidelines on ACs, as well as provides an important opportunity to develop better treatment strategies for reducing, or even preventing pain.