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Discovery of potent and selective urea-based ROCKinhibitors: Exploring the inhibitor's poten
ISSN号:0968-0896
期刊名称:Bioorganic & Medicinal Chemistry
时间:2015
页码:2505-2517
相关项目:新型氟代HMG-CoA还原酶抑制剂的设计与合成
作者:
Hong Zhou|Guofeng Sun|Yu Jiang|Yangbo Feng|
同期刊论文项目
新型氟代HMG-CoA还原酶抑制剂的设计与合成
期刊论文 36
会议论文 4
同项目期刊论文
A Green and Novel Method for the Synthesis of 4,4-Difluoro-3-oxo-2-(triphenylphosphoranylidene) delt
A Convenient Synthesis of 3-Aryl-4-fluoroalkyl-2-oxazolidinone
Synthesis of g,g-difluoro-b-hydroxy-d-lactones as new precursors of HMG-CoA reductase inhibitor
Synthesis of 1,3,5-Trisubstituted [4-tert-Butyl 2-(5,5-difluoro- 2,2-dimethyl-6-vinyl-1,3-dioxan-4-y
One-Pot Addition–Intramolecular N-Cyclization of Carbamates Mediated by Alkali Metallic Re
A Green and Novel Method for the Synthesis of 4,4-Difluoro-3- oxo-2-(triphenylphosphoranylidene) &am
Regioselective nucleophilic addition of 3-aryl-5-difluoromethyl-isoxazoles to aldehydes.
Synthesis andin vitro antibacterial activity of novel fluoroalkyl-substituted pyrazolyl oxazolidinon
Enantioselective Reformatsky Reaction between Cinnamaldehyde and Diflurinated Organozinc R
Molecular modeling studies of atorvastatin analogues as HMGR inhibitors using 3D-QSAR, molecular doc
3D-QSAR and Docking Studies on 2-acyliminobenzimidazoles Derivatives as Potent ALK Inhibitors
Organocatalytic Asymmetric Michael Addition/Carbon-Carbon Bond Cleavage of Trifluoromethyl alpha-Flu
Synthesis of 1,3,5-Trisubstituted [4-tert-Butyl 2-(5,5-difluoro-2,2-dimethyl-6-vinyl-1,3-dioxan-4-yl
A novel chemodosimeter for fluoride ions based on deprotonation of the C–H group followed
The research for introducing gem-difluoromethylene group into the organic molecules.
一种有效合成3-芳基-4-氟烷基-2-噁唑烷酮的方法
一种有效合成5-氟烷基噁唑啉的方法
Synthesis of Fluoroalkylated Allylic-β-hydroxyesters and Fluoroalkylated β,&ga
Crystalstructure and mechanistic investigation of the reaction of5-amino-1-(2,6-dichloro-4-(trifluor
HighlyRegio- and Diastereoselective Addition of Organolithium Reagents to ChiralFluoroalkyl α,β-Unsa
cRGDyK-modified camretastain A4-loaded grapheneoxide nanosheets for targeted anticancer drug deliver
Synthesis of difluoroalkyl-γ-butyrolactones fromiododifluoromethyl ketones and 4-pentenoic acids
A metal-free and recyclablesynthesis of benzothiazoles using thiourea as a sulfur surrogate
Derivativesof α,α-aryl Naphthalimide Nitriles as Fluoride ion Sensors, Convenient Precursors for the
Microwave-assisted expeditious synthesis of 5-fluoroalkyl-3-(aryl/alkyl)-oxazolidin-2-ones
Synthesis of 1,3,5-Trisubstituted [4-tert-Butyl 2-(5,5-difluoro- 2,2-dimethyl-6-vinyl-l,3-dioxan-4-yl)acetate]pyrazoles via a Pd-Catalyzed C--H Activation
Synthesis of Fluoroalkylated Allylic-β-hydroxyesters and Fluoroalkylated ,β,γ-Epoxy Esters from Ethyl 3-Hydroxy-4-pentenoate
A Green and Novel Method for the Synthesis of 4,4-Difluoro-3- oxo-2-(triphenylphosphoranylidene) 5-Lactones by Reformatsky Reaction
铜参与的三氟甲硫化反应研究进展