中文摘要：

哺乳动物的生殖活动受到神经内分泌系统的精确调控。近年来的研究表明,KISS-1基因的表达产物Kisspeptins及其G蛋白偶联受体（G protein coupled receptor 54,GPR54）在这一调控网络中发挥着重要作用,与哺乳动物青春期启动、发情排卵及季节性繁殖等过程密切相关。该文就近年来Kisspeptins/GPR54系统对哺乳动物生殖活动调控的研究进展进行简述。

英文摘要：

The reproduction of mammal is controlled by a network which composed of neuro-endocrine system. The recent research has demonstrated that Kisspeptins, the protein of KISS-1 gene, and its receptor GPR54 play important roles in this neuro-endocrine network, and have intimate relationship with the onset of puberty, oestrus and ovulation, the switching of oestrus and anestrus of seasonal reproduction animal. Here, the recent research progress of Kisspeptins/GPR54 system in the mammal reproduction regulation is reviewed.