中文摘要：

目的：分析研究皂帽花果实挥发油的主要成分及其抗肿瘤活性。方法：采用水蒸气蒸馏法从皂帽花果实中提取挥发油，利用气相色谱－质谱对其化学成分进行分析。MTT（四甲基偶氮唑盐）法检测皂帽花提取物对细胞SPCA－1、BEL-7402、SGC-7901和K－562增殖抑制作用。结果：分离出55个峰，鉴定出30种化学成分，占挥发油总量的74．98％。其中主要成分为橙花叔醇（19．887％）、石竹烯（16．714％）和口．月桂烯（9．29％）。抗肿瘤活性结果表明皂帽花果实挥发油对4种肿瘤细胞株均显示一定的抑制活性，其中对肺腺癌细胞SPCA．1的抑制活性最强，其IC50值为6．61μg/mL。结论：该实验为皂帽花的进一步开发研究提供了科学依据。

英文摘要：

Objective：To study the chemical components and antitumor activities of essential oil from the fruits of Dasymaschalon trichophorum. Methods ： The essential oil from the fruits of Dasymaschalon trichophorum was extracted by steam-stilling and analyzed by GC-MS. The inhibitory effect of extract ofDasymaschalon trichophorum on SPCA-1 ,BEL-7402,SGC-7901 and K-562 cell proliferation was assayed using the MTF. Results ： GC-MS result showed that there were 55 peaks and 30 compounds were identified which weighed 74. 98%. The major components were nerolidol（ 19. 887% ） ,caryophyllene（ 16. 714% ）and ]3-myrcene（9. 29% ）. The essential oil exhibited strong antitumor activity against SPCA-1 human tumor cell line with IC50 value of 6. 61 μg/mL. Conclusion： This experiment provides scientific foundation for further utilization of Dasymaschalon trichophorum.