中文摘要：

急性肾损伤是一组以急性肾功能减退为特征的临床综合征，是危重症患者的常见并发症之一，治疗棘手，病死率高。临床上大多数使用血肌酐和尿量作为急性肾损伤的诊断标准，不能及时和准确反映肾功能变化。目前一些新的生物学标记物的出现为急性肾损伤的早期诊断和治疗提供了可能，本文就目前研究较热的几种生物学标记物作一简单综述。

英文摘要：

Acute kidney injury （AKI） is a clinical syndrome characterized as acute renal dysfunction with difficult treatment and high mortality, and is one of the most common complications in critically ill pa- tients. Till now, the blood creatinine and urine volume were widely used to diagnose AKI in clinic, but both of them could not represent the change of renal function timely and accurately. Some new biomarkers provide new probable criteria for early diagnosis and treatment of AKI. In this paper, we make a review on new bio- logical markers focused on AKI research at present.