中文摘要：

目的探讨肝脏嗜酸性粒细胞浸润（EHI）的CT、MRI特征。方法回顾性分析经穿刺病理活检或临床确诊为肝脏EHI且行CT和（或）MRI检查的29例患者。27例行上腹部CT平扫及三期增强扫描，5例行上腹部MR平扫和三期增强扫描，其中3例同时行CT及MRI检查。观察病灶数目、分布、大小、形态、边缘、密度或信号、强化特点等表现。采用Pearson相关分析评价肝内病灶数目与外周血嗜酸性粒细胞数量相关性。结果单发病灶2例，多发病灶27例，共检出病灶108个。外周血嗜酸性粒细胞计数为1．53×10^9～40．16×10^9／L，中位数为13．28×10^9／L。病灶数目与嗜酸性细胞计数呈正相关（r=0．783，P〈0．05）。病灶最大径为3～61mm，中位最大径34mm，病灶边界均显示不清晰。病灶主要分布于肝包膜下（43个）或门静脉周围的肝实质（52个）内，少量位于深部肝实质（13个）。肝包膜下病灶多为楔形（28个），门静脉周围病灶多为圆形或类圆形（32个），深部肝实质病灶多为不规则形（8个）或类圆形（5个）。CT平扫病灶表现为低、等密度；MRI平扫，T1WI呈等、低信号，T2WI表现为等、高信号，以高信号为主。三期增强扫描病灶呈渐进性强化，29例均可见“门静脉穿行征”，12例可见“条带征”，16例可见“晕环征”。结论肝脏EHI影像表现具有一定特征性，渐进性强化、“门静脉穿行征”、“条带征”和“晕环征”是其主要表现。

英文摘要：

Objective To study and analyze the CT and MRI findings of hepatic eosinophilic infiltration. Methods Twenty nine patients of hepatic eosinophilic infiltration who were confirmed by biopsy or clinical diagnosis were retrospectively analyzed. All the patients underwent CT and/or MRI scan. Twenty seven cases underwent upper abdominal CT plain scan and three phase enhanced scan, and 5 cases underwent upper abdominal MR plain scan and three phase enhanced scan, of which 3 cases underwent CT and MRI scan. Evaluations were made regarding to the numbers of lesion, distribution, size, shape, margin, density or signal characteristic, enhancement parttern and other special features. Pearson correlation analysis was used to analyze the correlation between the number of hepatic lesions and the number of eosinophils in peripheral blood. Results A total of 108 lesions of eosinophilic hepatic infiltration were observed in 29 cases, including 2 cases with single lesion and 27 cases with multiple lesions. Ninety five of the lesions were located in subcapsular parenchyma or surrounding the portal vein. Most subeapsular lesions were wedge-shaped （n=28）. Lesions surrounding portal vein were round-shaped （n=32）, while the hepatic parenchymal lesions were irregular or round-shaped （n=13）. The mean size of lesion was 34 mm, ranging from 3 to 61 mm. The margin of all the lesions were obscure. The lesions showed slightly low density or isodensity on CT pre-contrast images. On MR pre-contrast images, lesions showed slightly low signal or isointense on T1WI, and hyperintense on T~WI. Branches of portal vein were found infilrated by all lesions. Tueleve cases showed ＂stripe sign＂ along the portal vein branches, 16 cases showed ＂halo ring sign＂ around the portal vein. Pearson analysis indicated a significant correlation between the number of eosinophilic hepatic infiltrated lesions and the increase of eosinophils in peripheral blood （r=0.783, P〈0.05）. Conclusion The imaging features of EHI had certain characteristics