位置:成果数据库 > 期刊 > 期刊详情页
融水小型猪F1代的血常规、血生化与电解质指标
  • ISSN号:1671-7856
  • 期刊名称:《中国比较医学杂志》
  • 时间:0
  • 分类:R332[医药卫生—人体生理学;医药卫生—基础医学]
  • 作者机构:[1]广东省医学实验动物中心,佛山528248, [2]广东贝格生物科技有限公司,佛山510642, [3]广州医药工业研究总院,广州510240, [4]佛山科技学院,佛山528231, [5]广东省医学科学院,广州510060
  • 相关基金:国家自然科学基金重点项目(81120108003;81330007)
中文摘要:

目的测定融水小型猪(rongshui miniature pig,RMP)F1代血常规、血生化与电解质指标。方法选取4月龄F1代RMP 85头,雌性43头、雄性42头;12月龄36头,雌雄各半。颈静脉采血,分析血常规、血生化与电解质等22项指标。结果融水小型猪相同月龄时,两性别的血常规指标、血生化和电解质的大部分指标差异不大,但同性别在不同月龄之间的部分指标差异明显。12月龄比4月龄融水小型猪,血常规指标中的白细胞数、血小板数下降,血红蛋白含量升高(P〈0.05),而红细胞数变化不大(P〉0.05);血清ALT、AST、ALP、CK(雄性)、LDH(雄性)A/G、BUN、GLU(雌性)、CHOL(雄性)和K+下降(P〈0.05);血清总蛋白、TBIL、CR、Ca2+升高(P〈0.05),而血清CHOL(雌性)、TG,HDL-C,LDL-C变化不大。有19项生化、电解质指标在或接近人类正常值范围,占86.4%(19/22)。结论融水小型猪的部分血常规、大部分血生化与电解质指标与人类正常值接近。

英文摘要:

Objective To detect the blood parameter, blood biochemical and electrolyte indices of the F1 generation of Rongshui miniature pig (RMP). Methods The blood of 43 female and 42 male RMPs of 4'h month old, and 36 RMPs of 12th month old (half male and female) were extracted from jugular vein. And the blood parameter, blood biochemical and electrolyte indices were detected by blood analyzer and automatic biochemical analyzer. Results In the same month-old RMP, no significant difference between male and female were found in most indices of blood parameter,blood biochemical and electrolyte indices. On the other hand, many indices were difference between 4th month old and 12th month old RMPs of same gender. Compared with the 4th month old RMP, the 12th month old RMP decreased significantly in WBC and PLT, increased in HGB (P 〈 0.05) while RBC was the same (P 〉 0.05). Serum ALT, AST, ALP, CK (male), LDH(male), A/G, BUN, GLU (female), CHOL (male) and K+ decreased significantly (P 〈 0.05), while serum TP, TBIL, CR and Ca2+ increased significantly (P 〈 0. 05) ,but serum CHOL, TG, HDL-C and LDL-C were not different. 86.4% (19/22) biochemical and electrolyte indices in RMP were in/or close to the range of normal value of human. Conclusion Most of the blood parameter, blood biochemical and electrolyte indices of RMP were close to human' s normal value.

同期刊论文项目
同项目期刊论文
期刊信息
  • 《中国比较医学杂志》
  • 北大核心期刊(2014版)
  • 主管单位:中国科学技术协会
  • 主办单位:中国实验动物学会 中国医学科学院医学实验动物研究所
  • 主编:秦川
  • 地址:北京市朝阳区潘家园南里5号
  • 邮编:100021
  • 邮箱:b67761337@126.com
  • 电话:010-67779337
  • 国际标准刊号:ISSN:1671-7856
  • 国内统一刊号:ISSN:11-4822/R
  • 邮发代号:82-917
  • 获奖情况:
  • 中国科技论文统计源期刊
  • 国内外数据库收录:
  • 美国化学文摘(网络版),中国中国科技核心期刊,中国北大核心期刊(2014版)
  • 被引量:7696