中文摘要：

采用研磨法制备了3种不同化学计量比的喜树碱—七元瓜环固体包合物并通过紫外分光光度法考察了它们的包合率、溶解度和溶出速度。3种包合物的包合率都达到了80％以上，不同计量比的包合物使药物的溶解度和溶出速度有不同程度的提高，溶解度最大提高近261倍，在pH1．00盐酸溶液介质中10min内药物即可达到100％的溶出。

英文摘要：

During the experiment,we have made three camptothecin-cucurbit （n = 7）uril solid inclusion complexes whose mass ratio is different by using grinding method, and investigated their inclusion rate solubility、 dissolution rate. The inclusion rate of them is up to 80 pre cent, and the different mass rate inclusion make the solubility ,dissolution rate of comptothecin to improve in varying degrees,the maximum of the solubility is more than 261 times,and the dissolution rate of the drugs can reach 100 pre cent in pH1.00 hydrochloric acid medium within 10 min.