中文摘要：

在基于 microcantilever 的没有标签的 biodetection 技术，双 stranded DNA (dsDNA ) 分子的吸附在 Au 层上导致的偏转变化出现被 DNA biofilm 的机械、热、电的性质极大地影响。在这份报纸， dsDNA biofilm 的有弹性的性质被学习。首先， Parsegians 实验潜力基于一个 mesoscopic 液体水晶理论被采用在纹理粗糙的 DNA 柱体之中描述相互作用精力。就 DNA interaxial 距离的 Gaussian 分布而言，然后，认为的实验方法被用来第一次与一个随机的收拾行李模式为 DNA biofilm 的幼仔模量导出分析表情。结果证明 DNA biofilm 的那幼仔模量大概 10MPa。这些调查结果能提供一个简单、有效的方法在底层上评估软 biofilm 的机械性质。

英文摘要：

In microcantilever-based label-free biodetection technologies, deflection changes induced by adsorptions of double-stranded DNA （dsDNA） molecules on Au-layer surface are greatly affected by the mechanical, thermal and electrical properties of DNA biofilm. In this paper, the elastic properties of dsDNA biofilm are studied. First, the Parsegian＇s empirical potential based on a mesoscopic liq- uid crystal theory is employed to describe the interaction energy among coarse-grained DNA cylinders. Then, con- sidering a Gaussian distribution of DNA interaxial distance, the thought experiment method is used to derive an analyti- cal expression for Young＇s modulus of DNA biofilm with a stochastic packing pattern for the first time. Results show that Young＇s modulus of DNA biofilm is on the order of 10 MPa. These findings could provide a simple and effective method to evaluate the mechanical properties of soft biofilm on snbstrate.