位置:成果数据库 > 期刊 > 期刊详情页
Roux-en-Y gastric bypass promotes expression of PDX-1 and regeneration of β-cells in Goto-Kakizaki rats
  • ISSN号:1007-9327
  • 期刊名称:《世界胃肠病学杂志:英文版》
  • 时间:0
  • 分类:R656.6[医药卫生—临床医学;医药卫生—外科学]
  • 相关基金:Supported by The National Basic Research Program (973 Program),No 2007CB512705;; National Natural Science Foundation of China,No 30801464
中文摘要:

AIM:To study the effects of Roux-en-Y gastric bypass(RYGB) on the expression of pancreatic duodenal homeobox-1(PDX-1) and pancreatic β-cell regeneration/neogenesis,and their possible mechanisms in diabetics.METHODS:Three groups of randomly selected nonobese diabetic Goto-Kakizaki(GK) rats were subjected to RYGB,sham-RYGB and sham-operation(sham-op) surgery,respectively.The rats were euthanized at postoperative 1,2,4 and 12 wk.Their pancreases were resected and analyzed using reverse transcription polymerase...

英文摘要:

AIM:To study the effects of Roux-en-Y gastric bypass(RYGB) on the expression of pancreatic duodenal homeobox-1(PDX-1) and pancreatic β-cell regeneration/neogenesis,and their possible mechanisms in diabetics.METHODS:Three groups of randomly selected nonobese diabetic Goto-Kakizaki(GK) rats were subjected to RYGB,sham-RYGB and sham-operation(sham-op) surgery,respectively.The rats were euthanized at postoperative 1,2,4 and 12 wk.Their pancreases were resected and analyzed using reverse transcription polymerase...

同期刊论文项目
同项目期刊论文
期刊信息
  • 《世界胃肠病学杂志:英文版》
  • 主管单位:
  • 主办单位:百世登出版集团有限公司
  • 主编:
  • 地址:太原双塔西街77号
  • 邮编:100023
  • 邮箱:
  • 电话:0351-4078656
  • 国际标准刊号:ISSN:1007-9327
  • 国内统一刊号:ISSN:
  • 邮发代号:
  • 获奖情况:
  • 国内外数据库收录:
  • 美国化学文摘(网络版),英国农业与生物科学研究中心文摘,荷兰文摘与引文数据库,荷兰医学文摘,美国生物医学检索系统,美国科学引文索引(扩展库),日本日本科学技术振兴机构数据库,瑞典开放获取期刊指南
  • 被引量:12408